Global Next Generation Sequencing Sample Preparation Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

• In June 2024, Illumina Inc. successfully incorporated its newest chemistry, XLEAP-SBS™, for all reagents including NextSeq 1000 and NextSeq 2000 NGS instruments. It has established a top player position in DNA sequencing and array-based technologies. NextSeq 1000/2000 allows labs to conduct larger NGS projects without increasing costs, helping in the wider use of multiomic strategies.

• In June 2024, Beckman Coulter Life Sciences, expedited high-throughput genomic sample preparation workflows for instant results by introducing Biomek Echo One System. This solution offers flexible and integrated acoustic liquid handling for genomic workflows, such as NGS library sample preparation and high-throughput isothermal DNA assemblies.

In this report, the Global Next Generation Sequencing (NGS) Sample Preparation Market has been segmented by Workflow, Application, End-Use, and Geography. The segmentation by Workflow includes various stages involved in the sample preparation process such as library preparation, target enrichment, sample extraction, and quality control. These stages are critical in ensuring the accuracy and quality of sequencing data, driving the demand for advanced and efficient sample preparation techniques.

The market segmentation by Application includes clinical diagnostics, oncology, reproductive health, genetic screening, and others. Each application segment highlights the specific areas where NGS sample preparation is utilized, showcasing its wide-ranging impact on various fields of research and medicine. By focusing on these applications, the report provides insights into the diverse use cases and growing importance of NGS in advancing personalized medicine and improving patient outcomes.

The market is further segmented by End-Use into academic and research institutions, hospitals and clinics, pharmaceutical and biotechnology companies, and others. This segmentation underscores the broad adoption of NGS sample preparation technologies across different sectors, reflecting the increasing integration of NGS into routine clinical practice and cutting-edge research. Geographically, the report analyzes the market across major regions, providing a comprehensive view of regional trends, growth drivers, and market opportunities.

Global Next Generation Sequencing Sample Preparation Segment Analysis

In this report, the Global Next Generation Sequencing Sample Preparation Market has been segmented by Product & Service, Workflow, Application, End-Use and Geography.

Global Next Generation Sequencing Sample Preparation Market, Segmentation by Product & Service

The Global Next Generation Sequencing Sample Preparation Market has been segmented by Product & Service into Instruments, Consumables, and Services.

Instruments in the NGS sample preparation market refer to the sophisticated machinery and devices used to process and prepare biological samples before sequencing. These instruments include automated platforms for DNA/RNA extraction, fragmentation, and library preparation. Advanced instruments are designed to handle large volumes of samples with high precision, enabling faster throughput and reducing human error. They play a critical role in ensuring the quality and consistency of the samples, making them essential for high-throughput sequencing applications in research and clinical environments.

Consumables are another key segment of the market, encompassing the various reagents, kits, and tools used during the sample preparation process. Consumables are required for tasks such as DNA/RNA extraction, amplification, and purification, as well as for creating sequencing libraries. These consumables are used up during the preparation of samples and need to be replenished regularly. They include reagents like enzymes, primers, buffers, and library prep kits, which are crucial for obtaining high-quality sequencing data. As the volume of NGS testing grows, the demand for consumables is also rising, making it a significant segment in the market.

Services in the NGS sample preparation market refer to the support and expertise provided by service providers to assist in the preparation and analysis of samples. This can include contract research organizations (CROs), academic labs, and sequencing service providers offering sample processing, data analysis, and sequencing services. These services are often sought by organizations that may not have the necessary infrastructure or expertise to perform sample preparation in-house. They allow researchers and clinicians to outsource complex tasks, ensuring high-quality, accurate results without the need for significant investment in equipment and training.

The segmentation of the NGS sample preparation market into instruments, consumables, and services highlights the comprehensive nature of the industry, where each component works together to facilitate the seamless processing of samples for next-generation sequencing. The growing demand for precision and efficiency in genomic research, diagnostics, and clinical applications is driving continued innovation and expansion in each of these segments.

Global Next Generation Sequencing Sample Preparation Market, Segmentation by Workflow

The Global Next Generation Sequencing Sample Preparation Market has been segmented by Workflow into NGS Library Preparation Kits, Semi-automated Library Preparation, Automated Library Preparation and Clonal Amplification.

Semi-automated Library Preparation systems combine manual steps with automated processes, offering a balance between flexibility and efficiency. These systems are particularly useful for laboratories that handle a moderate volume of samples and require a certain degree of customization in their workflows. Automated Library Preparation systems, on the other hand, are fully automated platforms that significantly reduce hands-on time and minimize human error. These systems are ideal for high-throughput settings where large numbers of samples need to be processed consistently and accurately.

Clonal Amplification is a critical step in NGS sample preparation, involving the amplification of DNA or RNA fragments to generate sufficient quantities of material for sequencing. This step ensures that the sequencing process can be carried out with high accuracy and reliability, making it a vital component of the NGS workflow. Each of these segments plays a crucial role in the NGS sample preparation process, catering to different needs and scales of operation within research and clinical laboratories.

Global Next Generation Sequencing Sample Preparation Market, Segmentation by Application

The Global Next Generation Sequencing Sample Preparation Market has been segmented by Application into Oncology, Clinical Investigation, Reproductive Health, HLA Typing/Immune System Monitoring, Metagenomics, Epidemiology & Drug Development, Agrigenomics & Forensics and Consumer Genomics.

Oncology stands out as a prominent application area, wherein NGS sample preparation plays a crucial role in understanding the genetic basis of cancer and guiding personalized treatment strategies. Clinical Investigation encompasses a wide range of research and diagnostic activities, where NGS sample preparation facilitates the analysis of genetic variations associated with various diseases and conditions. Reproductive Health involves the use of NGS sample preparation techniques for preimplantation genetic testing, prenatal screening, and infertility treatment, enabling comprehensive genetic analysis to support reproductive decision-making. Additionally, applications such as HLA Typing/Immune System Monitoring, Metagenomics, Epidemiology & Drug Development, Agrigenomics & Forensics, and Consumer Genomics further demonstrate the versatility and utility of NGS sample preparation across diverse fields, including immunology, microbiology, agriculture, and personal genomics. These applications collectively drive the demand for advanced sample preparation technologies and solutions to address the evolving needs of researchers and clinicians worldwide.

Global Next Generation Sequencing Sample Preparation Market, Segmentation by End-Use

The Global Next Generation Sequencing Sample Preparation Market has been segmented by End-Use into Academic Research, Clinical Research, Hospitals & Clinics, Pharma & Biotech Entities and Other Users.

Academic Research institutes play a significant role in driving innovation and advancing genomic research, making them a key end-user segment for NGS sample preparation solutions. Clinical Research facilities utilize NGS sample preparation technologies to conduct studies aimed at understanding the genetic basis of diseases, identifying biomarkers, and developing targeted therapies, thereby contributing to advancements in precision medicine. Hospitals & Clinics increasingly integrate NGS-based diagnostics into their clinical workflows for applications such as cancer profiling, inherited disease testing, and infectious disease surveillance, driving the demand for efficient sample preparation tools tailored to clinical settings. Pharma & Biotech Entities leverage NGS sample preparation solutions for drug discovery, pharmacogenomics, and biomarker identification, supporting the development of novel therapeutics and personalized medicine approaches. Other Users encompass a diverse range of organizations, including government agencies, forensic laboratories, and agricultural research institutions, reflecting the broad applicability of NGS sample preparation across various sectors and disciplines. Collectively, these end-user segments fuel the growth of the global NGS sample preparation market by driving demand for high-quality, reliable sample preparation products and services tailored to their specific research and diagnostic needs.

Global Next Generation Sequencing Sample Preparation Market, Segmentation by Geography

In this report, the Global Next Generation Sequencing Sample Preparation Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.

Global Next Generation Sequencing Sample Preparation Market Share (%), by Geographical Region, 2024

These regions represent key markets for next-generation sequencing sample preparation solutions, with each region contributing to the overall growth and development of the market. North America, particularly the United States and Canada, holds a significant share of the market due to the presence of leading biotechnology and pharmaceutical companies, well-established research infrastructure, and supportive regulatory environment conducive to genomic research and innovation.

Europe boasts a robust life sciences industry and extensive network of academic and research institutions, driving the adoption of next-generation sequencing technologies for various applications. The Asia Pacific region, including countries like China, Japan, and India, is experiencing rapid growth in genomic research and personalized medicine initiatives, fueling demand for advanced sample preparation solutions. Additionally, emerging economies in Latin America and the Middle East and Africa are increasingly investing in healthcare infrastructure and research capabilities, presenting untapped opportunities for market expansion. Overall, the global spread of next-generation sequencing sample preparation market players underscores the widespread adoption and importance of genomic technologies in advancing scientific understanding and improving healthcare outcomes worldwide.

This report provides an in depth analysis of various factors that impact the dynamics of Global Next Generation Sequencing Sample Preparation Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.

Drivers, Restraints and Opportunity Analysis

Drivers :

• Increasing adoption of NGS across various fields
• Falling costs of NGS procedures

• Advancements in NGS technology - Advancements in Next Generation Sequencing (NGS) technology have been instrumental in driving innovations in sample preparation methods, thereby shaping the landscape of the global NGS sample preparation market. One notable area of advancement is the development of highly efficient and streamlined workflows for sample preparation. Manufacturers have introduced integrated systems and kits that offer automation, standardization, and scalability, enabling researchers to process samples with greater speed and precision. These advancements have significantly reduced hands-on time and minimized human error, enhancing the reproducibility and reliability of NGS data generation.

  Technological innovations have expanded the range of applications for NGS sample preparation across diverse research fields and clinical settings. Novel methodologies and protocols have been devised to address specific sample types, such as low-input and degraded samples, enabling researchers to extract meaningful genomic information from challenging sample sources. Additionally, advancements in library preparation techniques, such as single-cell sequencing and spatial transcriptomics, have enabled high-resolution analyses of complex biological systems at unprecedented scales. These technological breakthroughs have opened up new avenues for exploring genomic heterogeneity, deciphering disease mechanisms, and identifying potential therapeutic targets, driving the adoption of NGS sample preparation solutions across various domains.

Restraints :

• Ethical and privacy concerns

• Shift towards personalized medicine - The Global Next Generation Sequencing (NGS) Sample Preparation Market is experiencing a significant shift towards personalized medicine, driven by advancements in genomic research and healthcare technologies. Personalized medicine aims to tailor medical treatments and interventions to individual patients based on their genetic makeup, disease characteristics, and lifestyle factors. NGS sample preparation plays a crucial role in enabling personalized medicine by facilitating the sequencing and analysis of patient genomes to identify genetic variations, disease markers, and treatment responses.

  This shift towards personalized medicine is fueled by several factors. Firstly, the declining costs of NGS technologies have made genomic sequencing more accessible, allowing healthcare providers to incorporate genetic testing into routine clinical practice. Additionally, the growing understanding of the genetic basis of diseases, coupled with advancements in bioinformatics and data analysis tools, has enabled researchers and clinicians to interpret genomic data more accurately and derive actionable insights for patient care.

  The emergence of targeted therapies and precision diagnostics that leverage genomic information to guide treatment decisions has spurred the adoption of NGS sample preparation in clinical settings. By identifying specific genetic mutations or biomarkers associated with diseases, NGS enables clinicians to prescribe targeted therapies that are more effective and less toxic, leading to improved patient outcomes.

  The shift towards personalized medicine represents a paradigm shift in healthcare, with NGS sample preparation playing a central role in driving innovation and transforming the delivery of precision medicine solutions tailored to individual patient needs. As personalized medicine continues to gain momentum, the demand for advanced NGS sample preparation technologies and services is expected to grow, driving further expansion of the global market.

Opportunities :

• Technological advancements

• Focus on automation - The Global Next Generation Sequencing (NGS) Sample Preparation Market is witnessing a notable focus on automation, driven by the need for enhanced efficiency, reproducibility, and scalability in genomic workflows. Automation in NGS sample preparation streamlines processes, reduces manual labor, minimizes human error, and accelerates turnaround times, thereby optimizing laboratory workflows and increasing productivity. Automated sample preparation systems offer advantages such as precise liquid handling, standardized protocols, and workflow integration, enabling laboratories to handle large sample volumes and complex assays with ease. Moreover, automation enables seamless integration with downstream NGS platforms, ensuring compatibility and data integrity throughout the sequencing process. As laboratories increasingly adopt high-throughput NGS technologies for applications such as clinical diagnostics, population genomics, and drug discovery, the demand for automated sample preparation solutions is expected to surge. Market players are innovating and expanding their product portfolios to offer advanced automated sample preparation platforms equipped with features such as robotic pipetting, magnetic bead-based purification, and real-time monitoring, catering to the evolving needs of researchers and clinicians. Overall, automation remains a key focus area in the NGS sample preparation market, driving efficiency, standardization, and cost-effectiveness across genomic workflows.

Key players in Global Next Generation Sequencing Sample Preparation Market include

• Illumina, Inc
• F. Hoffmann-La Roche Ltd
• Agilent Technologies, Inc
• PierianDx
• Eurofins Scientific
• Oxford Nanopore Technologies
• Quest Diagnostics Incorporated
• Foundation Medicine, Inc
• Macrogen, Inc
• Thermo Fisher Scientific, Inc
• QIAGEN
• BGI
• Perkin Elmer, Inc
• Pacific Biosciences of California, Inc
• Bio-Rad Laboratories, Inc
• Myriad Genetics, Inc
• LGC Limited
• Vela Diagnostics

In this report, the profile of each market player provides following information:

• Company Overview and Product Portfolio
• Key Developments
• Financial Overview
• Strategies
• Company SWOT Analysis