Global Gut Health Supplements Market Growth, Share, Size, Trends and Forecast (2025 - 2031)

• In April 2023, Centrum expanded into a new line of high-science supplements in a flavorful gummy format for varied benefits.

• In August 2022, Megalabs USA, a subsidiary of Megalabs Inc. that manufactures, markets, and distributes pharmaceutical products and nutritional supplements throughout the Americas, launched Glutapak R, a probiotic glutamine supplement for gut health and intestinal healing.

The digestive health market is categorized by product type, including prebiotics, probiotics, digestive enzymes, polyphenols, and other related products. Prebiotics and probiotics continue to lead the market due to their proven benefits in promoting gut health and preventing gastrointestinal issues. Digestive enzymes are gaining attention as a solution for individuals dealing with specific food intolerances and digestion problems. Polyphenols, recognized for their antioxidant and anti-inflammatory properties, are being integrated into health products for broader benefits that extend beyond digestion.

The market is further segmented by distribution channel, comprising over-the-counter (OTC) and prescribed products. OTC products dominate this segment, driven by the increasing availability of digestive health solutions in supermarkets, pharmacies, and online platforms. These products are preferred by consumers for their convenience and ease of access, particularly for general gut health maintenance. On the other hand, prescribed digestive health products focus on addressing chronic or severe digestive disorders, such as irritable bowel syndrome or enzyme deficiencies, where medical guidance is essential.

The growing awareness of the importance of gut health is propelling innovation and the expansion of distribution channels. Online retail has emerged as a key platform, especially for OTC products, offering consumers a wider range of choices and detailed product information. Prescribed products benefit from advancements in medical research, leading to the development of more effective and targeted treatments. This dual-channel approach ensures that the market caters to both preventive wellness enthusiasts and individuals with specific medical needs, supporting its robust growth trajectory.

Global Gut Health Supplements Segment Analysis

In this report, the Global Gut Health Supplements Market has been segmented by Product, Distribution Channel and Geography.

Global Gut Health Supplements Market, Segmentation by Product

The global gut health supplements market is segmented by product into Prebiotics, Probiotics, Digestive Enzymes, Polyphenols and Others.

Probiotics are live microorganisms that confer health benefits when consumed in adequate amounts. They play a crucial role in supporting digestive function by replenishing beneficial bacteria in the gut, aiding in the breakdown of food substances, and contributing to immune health. Common probiotic strains include lactobacilli and bifidobacteria, which are found in fermented foods like yogurt and in probiotic supplements designed to deliver specific health benefits. Digestive enzymes are another segment in the market that helps break down macronutrients such as proteins, fats, and carbohydrates into smaller molecules that the body can absorb. Enzymes like amylase, protease, and lipase are naturally produced in the body and are also available in supplement form to support individuals with digestive disorders or insufficient enzyme production. Polyphenols, derived from plants, are antioxidant compounds known for their anti-inflammatory properties and beneficial effects on gut health. They contribute to reducing oxidative stress in the digestive tract and supporting the growth of beneficial gut bacteria. Polyphenols are commonly found in foods like berries, green tea, and dark chocolate, as well as in supplements aimed at promoting digestive wellness and overall health. The "Others" category encompasses various bioactive compounds and ingredients that also contribute to gut health, such as herbal extracts, omega-3 fatty acids, and dietary fibers beyond prebiotics. This diverse segmentation of the gut health supplements market reflects the growing consumer interest in maintaining digestive health through natural and scientifically-backed ingredients, driving innovation and product development across the industry.

Global Gut Health Supplements Market, Segmentation by Distribution Channel

The global gut health supplements market is segmented by distribution channel into OTC and Prescribed.

In contrast, prescribed gut health supplements are recommended by healthcare professionals, including doctors, gastroenterologists, and nutritionists, based on specific health conditions or individual health assessments. These products often contain higher concentrations of active ingredients or specialized formulations tailored to address severe digestive disorders or deficiencies requiring medical supervision. Prescribed supplements are commonly dispensed through pharmacies under professional guidance, ensuring appropriate usage and monitoring of health outcomes. The segmentation into OTC and prescribed distribution channels reflects varying consumer needs and regulatory considerations governing the sale and promotion of gut health supplements. While OTC supplements offer convenience and flexibility in self-management of digestive health, prescribed supplements provide targeted therapeutic benefits and personalized care under healthcare supervision. Both distribution channels contribute to the accessibility and diversity of gut health supplements in meeting global demand for digestive wellness solutions.

Global Gut Health Supplements Market, Segmentation by Geography

In this report, the Global Gut Health Supplements Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.

Global Gut Health Supplements Market Share (%), by Geographical Region, 2024

North America holds a significant share due to high consumer awareness and adoption of dietary supplements aimed at improving digestive health. The region benefits from robust healthcare infrastructure and a well-established market for both over-the-counter (OTC) and prescribed gut health supplements, driven by a proactive approach to wellness and preventive healthcare.

Europe follows closely, characterized by stringent regulatory frameworks that ensure product safety and efficacy in the gut health supplements market. Consumer demand in Europe is fueled by a preference for natural and scientifically validated products, emphasizing quality and transparency in ingredients. The region sees a growing trend towards personalized nutrition solutions, influencing product innovation and the development of tailored supplements catering to diverse digestive health needs.

In the Asia-Pacific region, rapid urbanization, changing dietary habits, and increasing disposable incomes contribute to the expanding market for gut health supplements. Countries like China, Japan, and India are witnessing a surge in consumer interest in digestive wellness products, driven by rising health consciousness and a shift towards preventive healthcare practices. This region presents opportunities for market growth, supported by a growing middle-class population seeking effective solutions for digestive discomforts and maintaining gut microbiota balance.

Latin America and the Middle East & Africa regions are emerging markets in the global gut health supplements landscape, characterized by evolving healthcare infrastructures and increasing consumer awareness of digestive health benefits. These regions offer untapped potential for market expansion, driven by improving economic conditions, urbanization, and expanding distribution channels that facilitate wider access to supplements. Overall, the segmentation by geography highlights diverse regional dynamics and growth opportunities in the global gut health supplements market, influenced by varying consumer behaviors, regulatory landscapes, and healthcare trends.