Global Cyclodextrins Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Product Type;
α-Cyclodextrin, β-Cyclodextrin, γ-Cyclodextrin, and Others (Hydroxypropyl and Methylated).By Grade;
Food Grade and Pharmaceutical Grade.By End-Use Industry;
Food & Beverage, Pharmaceuticals, Cosmetics & Personal Care, Chemicals, Packaging, and Others (Agriculture and Biotechnology).By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2020 - 2030).Introduction
Global Cyclodextrins Market (USD Million), 2021 - 2031
In the year 2024, the Global Cyclodextrins Market was valued at USD 183.24 million. The size of this market is expected to increase to USD 254.43 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 4.8%.
Cyclodextrins, a family of cyclic oligosaccharides, have garnered significant attention across various industries due to their unique molecular structure and versatile properties. These cyclic molecules are composed of glucose units linked together in a ring shape, forming a hydrophobic cavity and a hydrophilic exterior. This unique structure enables cyclodextrins to form inclusion complexes with guest molecules, trapping them within their cavity and altering their physicochemical properties. This property makes cyclodextrins invaluable in numerous applications, ranging from pharmaceuticals to food and fragrance industries.
In the pharmaceutical sector, cyclodextrins play a pivotal role in improving the solubility, stability, and bioavailability of poorly soluble drugs. By encapsulating hydrophobic drug molecules within their cavity, cyclodextrins can enhance their aqueous solubility, facilitating better absorption in the body and improving therapeutic outcomes. Moreover, cyclodextrins serve as excipients in drug formulations, aiding in the controlled release of active pharmaceutical ingredients and minimizing side effects. These applications have made cyclodextrins indispensable in modern drug delivery systems, contributing to advancements in pharmaceutical research and development.
Cyclodextrins find extensive use in the food and beverage industry. As encapsulating agents, cyclodextrins can trap volatile flavors and aromas, thereby enhancing the stability and shelf life of food products. Additionally, cyclodextrins can be employed to mask undesirable tastes or odors, improving the overall sensory experience of food products. Their ability to form inclusion complexes with food additives and ingredients also enables the controlled release of flavors, colors, and nutrients, offering opportunities for innovation in food formulation and product development. As consumer preferences for natural and functional ingredients continue to drive innovation in the food industry, cyclodextrins remain a key ingredient for manufacturers seeking to meet these evolving demands.
Global Cyclodextrins Market Recent Developments
- In February 2021, RotaChrom Technologies and Cyclolab Cyclodextrin Research & Development Laboratory Ltd. have announced a collaborative partnership. The aim of this partnership is to develop a more efficient and cost-effective method for purifying Remdesivir, a widely used therapy for COVID-19.
- In March 2020, The antiviral drug Remdesivir (GS-5734), marketed under the brand name "Veklury," was discovered and developed by the American biotech company Gilead Sciences, Inc. specifically for treating COVID-19 infections.
Segment Analysis
The cyclodextrins market offers a diverse range of product types, including α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and others such as hydroxypropyl and methylated cyclodextrins. Each type possesses unique properties and applications, driving demand across various industries. α-Cyclodextrin, for instance, is known for its ability to form inclusion complexes with guest molecules, making it valuable in pharmaceuticals for drug delivery and solubilization. β-Cyclodextrin, with its larger cavity size, finds extensive use in the food and beverage industry for encapsulating flavors, fragrances, and food additives to enhance stability and solubility. Meanwhile, γ-cyclodextrin offers a larger cavity size than β-cyclodextrin, enabling it to encapsulate larger guest molecules, thus finding applications in industries such as cosmetics and personal care for stabilizing and delivering active ingredients.
In terms of grade, cyclodextrins are typically categorized as food grade and pharmaceutical grade. Food-grade cyclodextrins adhere to strict regulatory standards and are safe for consumption, making them suitable for use in the food and beverage industry. These cyclodextrins are utilized as food additives, flavor enhancers, and stabilizers, contributing to improved product quality and sensory attributes. On the other hand, pharmaceutical-grade cyclodextrins undergo stringent quality control measures to ensure purity, safety, and efficacy. These high-quality cyclodextrins play a crucial role in pharmaceutical formulations, aiding in drug solubilization, bioavailability enhancement, and controlled release.
The end-use industries for cyclodextrins span a wide spectrum, including food and beverage, pharmaceuticals, cosmetics and personal care, chemicals, packaging, and others such as agriculture and biotechnology. In the food and beverage industry, cyclodextrins are utilized as encapsulating agents, flavor carriers, and stabilizers to improve product formulations and sensory attributes. In pharmaceuticals, cyclodextrins serve as versatile excipients for enhancing drug solubility, stability, and bioavailability, thereby facilitating the development of novel drug delivery systems. Similarly, in cosmetics and personal care products, cyclodextrins function as encapsulating agents for active ingredients, contributing to the efficacy and stability of skincare, haircare, and fragrance formulations. Moreover, cyclodextrins find applications in chemicals for complexation, separation, and catalysis processes, as well as in packaging for odor control and barrier enhancement. The versatility of cyclodextrins across multiple industries underscores their significance as key ingredients in various applications, driving market growth and innovation.
Global Cyclodextrins Segment Analysis
In this report, the Global Cyclodextrins Market has been segmented by Product Type, Grade, End-use Industry and Geography.
Global Cyclodextrins Market, Segmentation by Product Type
The Global Cyclodextrins Market has been segmented by Product Type into α-Cyclodextrin, β-Cyclodextrin, γ-Cyclodextrin, and Others (Hydroxypropyl, Methylated).
In 2021, the Beta Oil segment emerged as the dominant force in the cyclodextrins market, capturing a substantial share of 42.6% and generating a market revenue of $115.23 million. This segment's significant market presence can be attributed to various factors, including its affordability and widespread availability compared to other cyclodextrins. Particularly notable is the widespread use of beta cyclodextrin in the production of Remdesivir injectable medications. Beta cyclodextrin serves as a cost-effective alternative in pharmaceutical formulations, making it a preferred choice for drug manufacturers seeking to optimize production costs without compromising on quality.
Throughout the forecast period, the Beta segment is projected to maintain its leading position in the cyclodextrins market, fueled by its multifaceted applications and inherent advantages. Apart from its pharmaceutical applications, beta cyclodextrins are extensively utilized in the food industry to enhance the quality and sensory attributes of food products. Adding beta cyclodextrins to meals improves the appearance, taste, and overall attractiveness of the finished items. Moreover, beta cyclodextrins play a crucial role in food safety by preventing contamination and extending the shelf life of products, contributing to consumer confidence and satisfaction.
The incorporation of beta cyclodextrins in food products such as green tea drinks underscores their versatility and appeal in the food and beverage sector. Beta cyclodextrins innovate the sensory attributes of food items, enhancing their marketability and consumer acceptance. As consumer preferences continue to evolve towards natural and functional ingredients, the demand for beta cyclodextrins in food applications is expected to rise, further consolidating the segment's leading position in the cyclodextrins market.
Global Cyclodextrins Market, Segmentation by Grade
The Global Cyclodextrins Market has been segmented by Grade into Food Grade and Pharmaceutical Grade.
Food grade cyclodextrins are extensively utilized in the food and beverage sector as complexing agents, encapsulation agents, and flavor enhancers. These cyclodextrins, typically derived from natural starch sources, undergo rigorous purification processes to ensure they meet safety standards for human consumption. With increasing consumer demand for natural and functional food ingredients, food grade cyclodextrins play a vital role in improving the solubility, stability, and bioavailability of food additives, flavors, and nutritional supplements.
Pharmaceutical grade cyclodextrins are specifically designed and manufactured to meet the stringent quality standards mandated for pharmaceutical applications. These cyclodextrins undergo meticulous purification and quality control measures to ensure they are free from impurities and suitable for use in drug formulations. Pharmaceutical grade cyclodextrins serve as versatile excipients in pharmaceutical formulations, aiding in the solubilization, stabilization, and controlled release of drugs. Their ability to enhance the bioavailability and therapeutic efficacy of poorly soluble drugs makes them indispensable in the pharmaceutical industry, driving their demand among drug manufacturers and formulators worldwide.
The differentiation between food grade and pharmaceutical grade cyclodextrins underscores the critical importance of quality and safety considerations in their respective applications. While both grades share common properties and functions, their production processes and quality standards are tailored to meet the specific requirements of the food and pharmaceutical industries. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), impose strict regulations on the use of cyclodextrins in food and pharmaceutical products, necessitating compliance with Good Manufacturing Practices (GMP) and other quality assurance protocols.
As the demand for natural, safe, and effective ingredients continues to rise in both the food and pharmaceutical sectors, the market for cyclodextrins is expected to witness sustained growth. Manufacturers and suppliers of cyclodextrins are focusing on innovation, quality assurance, and regulatory compliance to meet the evolving needs of these industries and capitalize on emerging opportunities in the global market.
Global Cyclodextrins Market, Segmentation by End-use Industry
The Global Cyclodextrins Market has been segmented by End-User into Food & Beverage, Pharmaceuticals, Cosmetics & Personal Care, Chemicals, Packaging, and Others (Agriculture, Biotechnology).
The pharmaceutical segment stands out as the leading contributor to the cyclodextrin market, capturing a significant share of 30.6% in 2021, with a market revenue of $82.77 million. This dominance is expected to persist throughout the forecast period, driven by the indispensable role cyclodextrins play in enhancing the solubility and bioavailability of poorly soluble drugs. Within pharmaceutical and nutraceutical products, cyclodextrins serve as crucial components, facilitating the transformation of liquid medications into more stable forms, such as amorphous powders or microcrystalline structures. This characteristic makes them ideal for use in tablet formulations, contributing to improved drug delivery and efficacy.
Cyclodextrins offer pharmaceutical manufacturers a versatile solution to overcome the challenges associated with poorly soluble drugs. By encapsulating hydrophobic drug molecules within their cavity, cyclodextrins effectively increase the aqueous solubility of these compounds, enabling better absorption in the body and enhancing therapeutic outcomes. Furthermore, cyclodextrins play a vital role in mitigating the gastrointestinal side effects commonly associated with certain medications. Their ability to form inclusion complexes with drug molecules not only improves drug compatibility but also aids in reducing adverse reactions, thus improving patient compliance and treatment outcomes.
As pharmaceutical research continues to focus on developing novel drug formulations and delivery systems, the demand for cyclodextrins is expected to witness steady growth. The versatility, compatibility, and efficacy of cyclodextrins make them a preferred choice for pharmaceutical applications, driving their continued adoption in drug development and formulation processes. Additionally, as regulatory agencies emphasize the importance of enhancing drug solubility and bioavailability, cyclodextrins are poised to play an increasingly integral role in addressing these requirements and advancing pharmaceutical innovation.
Global Cyclodextrins Market, Segmentation by Geography
In this report, the Global Cyclodextrins Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Cyclodextrins Market Share (%), by Geographical Region, 2023
North America stands out as the largest market for cyclodextrin globally, capturing a substantial market share of approximately 32.2% and generating around $87.10 million in revenue in 2021. The dominance of North America in the cyclodextrin market can be attributed to several factors, including the region's robust pharmaceutical and nutraceutical industries. With a significant concentration of key players in these sectors, North America boasts a well-developed market for pharmaceutical and nutraceutical excipients, driving the demand for cyclodextrins. Despite experiencing slower growth compared to other regions, North America remains a lucrative market for cyclodextrins due to its established infrastructure and high spending capacity. Moreover, the busy and health-conscious lifestyles of North American consumers, coupled with the prevalence of chronic illnesses, further fuel the demand for cyclodextrins as essential components in dietary supplements and pharmaceutical formulations.
In contrast, the Asia Pacific market is poised to witness the fastest growth rate, expected to achieve a remarkable compound annual growth rate (CAGR) between 2021 and 2030. The increasing consumer demand for cyclodextrin molecules in medicinal applications drives the growth of the cyclodextrin market in the Asia Pacific region. Furthermore, the expansion of healthcare infrastructure and concerted government efforts aimed at improving healthcare access and affordability are key drivers propelling market growth in this region. As countries in Asia Pacific continue to experience rapid economic development and urbanization, there is a growing awareness of health and wellness, leading to an uptick in demand for pharmaceuticals and dietary supplements containing cyclodextrins.
The cyclodextrin market is characterized by dynamic growth prospects across different regions, with North America leading in terms of market share and revenue generation, while the Asia Pacific region emerges as a hotspot for future growth opportunities. As technological advancements continue to drive innovation and expand the applications of cyclodextrins in various industries, both regions are poised to play pivotal roles in shaping the trajectory of the global cyclodextrin market in the coming years.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Cyclodextrins Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers:
- Growing Applications in the Food and Beverage Industry
- Advancements in Drug Delivery Systems
- Increasing Investment in Healthcare Infrastructure
- High Consumption of Dietary Supplements -
As consumers become increasingly health-conscious and seek ways to enhance their well-being, the demand for dietary supplements continues to soar worldwide. Cyclodextrins play a crucial role in this trend as they are widely utilized as carriers or encapsulating agents for various bioactive compounds, including vitamins, minerals, and herbal extracts, in dietary supplement formulations. Cyclodextrins improve the stability, solubility, and bioavailability of these compounds, ensuring their effective delivery and absorption in the body. This functionality makes cyclodextrins indispensable in the production of high-quality dietary supplements that offer enhanced efficacy and consumer satisfaction.
Cyclodextrins address challenges associated with the formulation of dietary supplements, such as poor solubility and bioavailability of certain bioactive ingredients. By encapsulating hydrophobic or poorly soluble compounds within their cavity structure, cyclodextrins enable their dispersion in aqueous solutions and enhance their absorption in the gastrointestinal tract. This capability opens up opportunities for formulators to incorporate a broader range of beneficial ingredients into dietary supplements, thereby expanding product offerings and meeting diverse consumer needs. Additionally, cyclodextrins contribute to the development of innovative delivery systems, such as controlled-release formulations, further enhancing the attractiveness of dietary supplements to consumers seeking convenient and effective health solutions.
The global cyclodextrins market is poised to benefit from the continued growth of the dietary supplements industry, driven by factors such as increasing health awareness, aging populations, and lifestyle changes. As dietary supplement manufacturers strive to differentiate their products and meet evolving consumer preferences, cyclodextrins offer a versatile solution for improving formulation efficacy and product performance. Furthermore, the expanding market for functional foods and nutraceuticals presents additional opportunities for cyclodextrins, as they find applications beyond traditional dietary supplements in a variety of functional food and beverage products aimed at promoting health and wellness.
Restraints:
- Regulatory Challenges and Compliance Burdens
- Environmental Concerns and Sustainability Issues
- Intellectual Property Rights and Patent Constraints
- Fluctuations In Raw Material Prices -
Cyclodextrins are typically derived from starch, primarily corn, and the prices of these raw materials are subject to fluctuations influenced by factors such as weather conditions, agricultural practices, and global supply and demand dynamics. When raw material prices experience sudden spikes or volatility, it directly affects the production costs of cyclodextrins, leading to uncertainties in pricing and supply chain management for manufacturers. Consequently, such unpredictability can hinder investment decisions and long-term planning, restraining market growth.
The cyclicality of raw material prices also affects the pricing strategies of cyclodextrin-based products, making them less competitive in the market. When raw material costs surge, manufacturers may face pressure to increase prices to maintain profit margins, potentially deterring price-sensitive consumers from purchasing cyclodextrin-containing products. Moreover, the unpredictability in raw material prices can lead to inventory management challenges, as manufacturers may struggle to procure an adequate supply of affordable raw materials to meet production demands. This can result in production delays, inventory shortages, and ultimately, a loss of market share for cyclodextrin producers.
Fluctuations in raw material prices disrupt the global supply chain of cyclodextrins, affecting distribution networks and market accessibility. Manufacturers may encounter difficulties in sourcing consistent and cost-effective raw materials, especially in regions where supply chain infrastructure is underdeveloped or vulnerable to external disruptions. Consequently, supply chain inefficiencies can lead to delays in product delivery, increased transportation costs, and difficulties in meeting customer demands. Overall, the volatility in raw material prices poses a significant challenge to the global cyclodextrins market, requiring stakeholders to implement robust risk management strategies to mitigate the impact of price fluctuations.
Opportunities:
- Growing Demand in Pharmaceuticals and Drug Delivery Systems
- Enhanced Use in the Cosmetic and Personal Care Sector
- Increasing Utilization in the Chemical and Agricultural Industries
- Advancements in Biotechnology and Nanotechnology Applications -
Advancements in biotechnology and nanotechnology present significant opportunities for the global cyclodextrins market. Cyclodextrins, with their unique molecular structure and properties, are increasingly being utilized in various biotechnological applications. One key area is drug delivery, where cyclodextrins act as carriers for poorly soluble drugs, enhancing their solubility, stability, and bioavailability. With ongoing research and development in drug formulation, cyclodextrins offer a promising solution for improving the efficacy and delivery of pharmaceutical compounds, driving demand within the market.
Cyclodextrins find applications in nanotechnology, particularly in the development of nanoscale drug delivery systems. By encapsulating active pharmaceutical ingredients within cyclodextrin-based nanoparticles, researchers can achieve targeted and controlled release of drugs, minimizing side effects and improving therapeutic outcomes. This convergence of cyclodextrins and nanotechnology opens up new avenues for precision medicine, personalized therapies, and the treatment of complex diseases. As nanomedicine continues to advance, the demand for cyclodextrins as key components in nanocarriers is expected to surge, presenting lucrative opportunities for market growth.
Advancements in biotechnology are driving the expansion of cyclodextrins into other areas such as diagnostics, biocatalysis, and biomaterials. Cyclodextrins exhibit biocompatibility and non-toxicity, making them suitable for use in various biotechnological applications. In diagnostics, cyclodextrins are employed in sensor development for detecting biomarkers and analytes with high sensitivity and specificity. Additionally, in biocatalysis, cyclodextrins serve as versatile hosts for enzymes, facilitating enzymatic reactions in bioprocessing and synthesis. With ongoing research exploring the diverse capabilities of cyclodextrins in biotechnology and nanotechnology, the market is poised for sustained growth and innovation.
Competitive Landscape Analysis
Key players in Global Cyclodextrins Market include:
- Wacker Chemie AG.
- Ligand Pharmaceuticals Incorporated
- Roquette Freres
- Wellona Pharma Private Limited.
- Cambrex Corporation
- Cyclo Therapeutics Inc
- Cyclolab
- Tocopharm Co. Limited
- Midas Pharma GmbH
- Cayman Chemical Company
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product Type
- Market Snapshot, By Grade
- Market Snapshot, By End-use Industry
- Market Snapshot, By Region
- Global Cyclodextrins Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Growing Applications in the Food and Beverage Industry
- Advancements in Drug Delivery Systems
- Increasing Investment in Healthcare Infrastructure
- High Consumption of Dietary Supplements
- Restraints
- Regulatory Challenges and Compliance Burdens
- Environmental Concerns and Sustainability Issues
- Intellectual Property Rights and Patent Constraints
- Fluctuations In Raw Material Prices
- Opportunities
- Growing Demand in Pharmaceuticals and Drug Delivery Systems
- Enhanced Use in the Cosmetic and Personal Care Sector
- Increasing Utilization in the Chemical and Agricultural Industries
- Advancements in Biotechnology and Nanotechnology Applications
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitve Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Cyclodextrins Market, By Product Type, 2021 - 2031 (USD Million)
- α-Cyclodextrin
- β-Cyclodextrin
- γ-Cyclodextrin
- Others (Hydroxypropyl, Methylated)
- Global Cyclodextrins Market, By Grade, 2021 - 2031 (USD Million)
- Food Grade
- Pharmaceutical Grade
- Global Cyclodextrins Market, By End-use Industry, 2021 - 2031 (USD Million)
- Food & Beverage
- Pharmaceuticals
- Cosmetics & Personal Care
- Chemicals
- Packaging
- Others
- Agriculture
- Biotechnology
- Global Cyclodextrins Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Cyclodextrins Market, By Product Type, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Wacker Chemie AG.
- Ligand Pharmaceuticals Incorporated
- Roquette Freres
- Wellona Pharma Private Limited.
- Cambrex Corporation
- Cyclo Therapeutics Inc
- Cyclolab
- Tocopharm Co. Limited
- Midas Pharma GmbH
- Cayman Chemical Company
- Company Profiles
- Analyst Views
- Future Outlook of the Market