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Add to CartGlobal Cryopreservation Equipment Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Equipment;
Freezers - Cryopreservation Freezers and Drystore Freezers, Incubators, Sample Preparation Systems and Accessories - Cryopreservation Vials , Freezer Box, Cryocart, Cryogenic Vaporizer, and Others.By Application;
Cord Blood Stem Cells, Sperms, Semen & Testicular Tissues, Embryos & Oocytes, and Others.By End Users;
Stem Cells Banks, Biotechnology and Pharmaceutical Organizations , Contract Research Organizations, Stem Cell Research Laboratories, and Research and Academic Institutes.By Cryogen;
Liquid Nitrogen, Oxygen ,Argon, and Liquid Helium.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Cryopreservation Equipment Market (USD Million), 2021 - 2031
In the year 2024, the Global Cryopreservation Equipment Market was valued at USD 7,255.62 million. The size of this market is expected to increase to USD 15,063.84 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 11.0%.
Cryopreservation is a critical technique in the fields of biology and medicine, allowing for the long-term preservation of biological samples at ultra-low temperatures, typically below -150°C. This process effectively pauses biological and chemical processes, including those that could lead to cellular damage or death, thus enabling the storage of cells, tissues, and various biological molecules for extended periods without degradation. The utility of cryopreservation spans numerous applications, from the conservation of endangered species through the banking of their genetic materials, to the preservation of human embryos, sperm, and eggs in assisted reproductive technologies, and the maintenance of valuable cell lines for research and biomanufacturing.
The selection of cryoprotective agents (CPAs) and the method of cooling and warming are critical to the success of cryopreservation. CPAs are substances that protect biological material from damage due to ice formation during the freezing process. Commonly used CPAs include dimethyl sulfoxide (DMSO), glycerol, and ethylene glycol. These agents work by penetrating the cells and reducing the freezing point of the intracellular fluid, thus minimizing ice crystal formation that can rupture cell membranes. The process typically involves a controlled-rate freezing method that gradually lowers the temperature of the sample to prevent thermal shock and ensure uniform cooling, thereby enhancing the survival rates of cells or tissues upon thawing.
The cryogenic equipment used in cryopreservation is specialized to meet the varied requirements of different biological materials. For instance, cryopreservation freezers are designed to achieve and maintain the extremely low temperatures necessary for the long-term storage of biological samples, often using liquid nitrogen as a cooling agent. Liquid nitrogen vessels are used for the storage of cells and tissues in vapor or liquid phases, depending on the sensitivity of the samples to direct contact with liquid nitrogen. Cryogenic vaporizers allow for the controlled warming of samples, which is as critical as the cooling process because rapid temperature changes can be just as damaging. Furthermore, cryogenic incubators provide an environment for slowly thawing and recovering cells under optimal conditions, while liquid tracking equipment and cell freezing containers assist in the monitoring and handling of samples throughout the cryopreservation process.
The importance of cryopreservation in the advancement of biological sciences and medicine cannot be overstated. It not only enables the long-term storage and transportation of biological materials across the world but also facilitates advancements in genetic research, regenerative medicine, and biodiversity conservation. The development of new cryopreservation techniques and improvements in cryogenic equipment continues to expand the possibilities for preserving the viability and functionality of biological samples, paving the way for future scientific breakthroughs and therapeutic interventions.
Global Cryopreservation Equipment Market Recent Developments
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In August 2022, Medtronic Plc. acquired Affera, Inc., a leading company in cardiac ablation devices. This acquisition expanded Medtronic's cardiac ablation portfolio, incorporating Affera's cardiac mapping and navigation platform, as well as its radiofrequency and cryoablation technologies, thereby strengthening Medtronic's position in the growing cardiac ablation market.
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In February 2022, Medtronic Plc received U.S. FDA approval for its Freezor and Freezor Xtra cardiac cryoablation catheters to treat pediatric patients with atrioventricular nodal re-entrant tachycardia. This approval expanded Medtronic's customer base, contributing to the growth of its business revenue.
Segment Analysis
Cryopreservation and biobanking involve specialized equipment essential for preserving biological samples at ultra-low temperatures. This equipment includes various types of freezers, such as cryopreservation freezers designed for long-term storage at extremely low temperatures, and drystore freezers that maintain precise conditions to protect sensitive samples. Incubators are also integral, allowing for controlled sample handling and preparation before storage. Sample preparation systems and accessories, including cryopreservation vials, freezer boxes, cryocarts, and cryogenic vaporizers, support safe handling, organized storage, and efficient sample retrieval, ensuring that samples remain viable throughout the preservation process.
The applications of cryopreservation and biobanking span several biological materials, including cord blood stem cells, sperm, semen, testicular tissues, embryos, and oocytes. Cord blood stem cells are commonly preserved for future regenerative therapies, while cryopreservation of sperm and other reproductive tissues is often used in fertility treatments. Embryo and oocyte preservation is essential in assisted reproductive technologies, ensuring viable options for individuals undergoing treatments like IVF. The ability to store these diverse sample types supports advancements in personalized medicine, regenerative therapies, and reproductive health, making biobanking a critical resource for both clinical and research purposes.
End users of cryopreservation equipment include stem cell banks, biotechnology and pharmaceutical companies, contract research organizations (CROs), and stem cell research laboratories. These organizations rely on cryogenic storage to safeguard valuable biological samples for future use in research, clinical applications, and therapeutic development. Liquid nitrogen is the primary cryogen used for deep freezing, with liquid helium, oxygen, and argon as alternatives for specific applications. The availability of advanced cryopreservation equipment and cryogens enables long-term sample viability, supporting innovations in biotechnology, pharmaceutical development, and academic research by ensuring that high-quality biological materials are preserved effectively for future breakthroughs.
Global Cryopreservation Equipment Segment Analysis
In this report, the Global Cryopreservation Equipment Market has been segmented by Equipment, Application, End Users, Cryogen and Geography.
Global Cryopreservation Equipment Market, Segmentation by Equipment
The Global Cryopreservation Equipment Market has been segmented by Equipment into Freezers, Incubators, Sample Preparation Systems and Accessories.
Global Cryopreservation Equipment Market, Segmentation by Application
The Global Cryopreservation Equipment Market has been segmented by Application into Cord Blood Stem Cells, Sperms, Semen & Testicular Tissues, Embryos & Oocytes and Other Application.
One of the primary segments within this market is freezers, which are essential for storing biological samples at ultra-low temperatures. These freezers come in different configurations, including upright, chest, and portable units, offering versatility in accommodating different sample volumes and types. Advanced features such as programmable temperature settings, temperature alarms, and uniform cooling capabilities enhance the reliability and efficacy of sample storage, contributing to the widespread adoption of freezers across laboratories and biobanks worldwide.
Another key segment in the cryopreservation equipment market is incubators, which provide a controlled environment for the cultivation and maintenance of cell cultures and tissues. These incubators offer precise temperature, humidity, and gas control to mimic physiological conditions, supporting optimal cell growth and viability. With the increasing demand for cell-based research and regenerative medicine applications, the need for incubators equipped with cryopreservation capabilities is on the rise. These incubators facilitate the seamless integration of cryopreserved samples into cell culture workflows, enabling researchers to explore novel therapies and advance scientific discoveries.
Sample preparation systems and accessories constitute a crucial segment in the cryopreservation equipment market, encompassing a range of tools and consumables essential for sample processing and handling. These systems include centrifuges, cryogenic storage vials, cryoprotectants, and labeling solutions, among others, designed to ensure the efficient and safe storage of biological materials. Moreover, the integration of automation and robotics in sample preparation systems streamlines workflows, reduces manual errors, and enhances overall laboratory productivity. As researchers and clinicians increasingly focus on high-throughput cryopreservation and biobanking initiatives, the demand for robust sample preparation systems and accessories is expected to escalate, driving growth in this segment of the market.
Global Cryopreservation Equipment Market, Segmentation by End Users
The Global Cryopreservation Equipment Market has been segmented by End Users into Stem Cells Banks, Biotechnology and Pharmaceutical Organizations , Contract Research Organizations, Stem Cell Research Laboratories and Research and Academic Institutes.
One prominent application is the preservation of cord blood stem cells, which holds immense potential in regenerative medicine and treating various diseases. Cord blood stem cells are collected from the umbilical cord at birth and cryopreserved for future use, offering a valuable source of hematopoietic stem cells for transplantation therapies. This segment of the market is driven by increasing awareness about the therapeutic potential of stem cells and the growing prevalence of hematological disorders.
Another key application of cryopreservation equipment is the preservation of sperms, semen, and testicular tissues. Cryopreservation of male reproductive cells and tissues is crucial for fertility preservation, particularly for individuals undergoing cancer treatment or other medical procedures that may impair fertility. The advancements in assisted reproductive technologies (ART) have further propelled the demand for cryopreserved sperm and testicular tissues, offering new possibilities for fertility preservation and family planning.
Cryopreservation equipment finds extensive use in the preservation of embryos and oocytes (egg cells) for in vitro fertilization (IVF) procedures. IVF has become a widely accepted infertility treatment, and cryopreservation plays a pivotal role in enhancing the success rates of IVF cycles by allowing the storage and utilization of surplus embryos and oocytes. This segment of the market is driven by factors such as increasing infertility rates, delayed childbearing trends, and advancements in IVF techniques.
Cryopreservation equipment caters to various other applications, including the preservation of tissues, organs, and plant cells for research, transplantation, and agricultural purposes. With ongoing technological advancements and research initiatives, the scope of cryopreservation is expanding beyond traditional applications, driving the demand for specialized equipment tailored to specific needs. Overall, the segmentation of the global cryopreservation equipment market by application reflects the diverse array of uses and the growing importance of cryopreservation technology across multiple fields, from healthcare to agriculture and beyond.
Global Cryopreservation Equipment Market, Segmentation by Cryogen
The Global Cryopreservation Equipment Market has been segmented by Cryogen into Liquid Nitrogen, Oxygen , Argon and Liquid Helium.
Liquid nitrogen stands out as one of the most widely utilized cryogens in cryopreservation equipment. Its extremely low boiling point (-196°C) makes it ideal for creating and maintaining sub-zero temperatures necessary for long-term sample storage. Liquid nitrogen is commonly used in cryopreservation freezers and storage vessels, providing a cost-effective and reliable method for preserving a wide range of biological materials, from cells and tissues to embryos and genetic samples.
Oxygen, argon, and liquid helium also play essential roles in specific cryopreservation applications, albeit to a lesser extent compared to liquid nitrogen. Oxygen may be utilized in cryogenic incubators and sample preparation systems to maintain optimal conditions for cell cultures and biological reactions. Argon, with its inert properties, can be employed in specialized cryogenic environments for certain research and storage applications. Liquid helium, though less commonly used due to its higher cost and more complex handling requirements, finds niche applications in ultra-low temperature research and advanced cryopreservation techniques. Overall, the segmentation of cryopreservation equipment by cryogen reflects the diverse range of cryogenic substances employed in preserving biological samples and underscores the importance of selecting the most suitable cryogen for specific research and storage needs.
Global Cryopreservation Equipment Market, Segmentation by Geography
In this report, the Global Cryopreservation Equipment Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Cryopreservation Equipment Market Share (%), by Geographical Region, 2024
North America has emerged as a dominant force in the global cell cryopreservation market, owing to several key factors. The region benefits from the presence of major manufacturers of cryopreservation products, advanced medical infrastructure, and developed economies. These factors contribute to a conducive environment for the growth of the cell cryopreservation industry, facilitating research and development activities, as well as the commercialization of innovative solutions. Additionally, North America boasts significant players and well-established supply channels, further bolstering its market leadership. The increasing incidence of diseases and the expanding elderly population have fueled demand for innovative remedies, particularly within the biopharmaceutical industry. As a result, there is a growing need for cell cryopreservation technologies to support research, drug development, and therapeutic applications, driving revenue growth in the region.
The Asia Pacific region is poised to witness rapid growth in the cell cryopreservation market, fueled by various factors unique to the region. Countries like China and Japan are experiencing a surge in the adoption of cell cryopreservation technologies, driven by factors such as the large population size, increasing prevalence of chronic diseases, rising elderly population, and a notable increase in infertility rates. These demographic and healthcare trends create ample opportunities for the expansion of the cell cryopreservation industry in the Asia Pacific region. Additionally, advancements in healthcare infrastructure and increasing investments in research and development further contribute to the growth trajectory of the market. With a conducive market environment and rising demand for innovative healthcare solutions, the Asia Pacific region is expected to emerge as a key growth engine for the cell cryopreservation market in the coming years.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Cryopreservation Equipment Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunities
Drivers
- Advancements in Regenerative Medicine and Cell Therapy
- Rise in Biobanking Activities
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Increased Use in Assisted Reproductive Technology (ART): Cryopreservation plays a pivotal role in the realm of assisted reproductive technologies (ART), notably in vitro fertilization (IVF), by offering a way to pause the biological clock of gametes and embryos. This capability is especially significant against the backdrop of increasing infertility rates globally, which are driven by factors such as delayed parenthood, lifestyle changes, and environmental influences. The ability to store sperm, eggs, and embryos securely at cryogenic temperatures not only extends the reproductive options for individuals and couples but also enhances the success rates of ART procedures by allowing multiple attempts without the need for fresh extraction each time. Moreover, advancements in IVF techniques, such as the optimization of cryoprotocols and the development of more sophisticated freezing equipment, have significantly improved the survival and viability rates of thawed biological materials, thereby boosting the confidence in cryopreservation as a reliable component of fertility treatments.
The surge in demand for cryopreservation equipment is also a reflection of the broader acceptance and utilization of ART for family planning purposes. As society becomes more open to these technologies and as they become more accessible across different regions, the infrastructure to support ART, including state-of-the-art cryogenic storage solutions, becomes increasingly crucial. This growing demand is not only for the basic storage of biological materials but also for advanced monitoring and automation features that ensure the long-term stability and integrity of these materials. The evolution of cryopreservation equipment, with enhancements in safety, efficiency, and reliability, is essential in meeting the expanding needs of fertility clinics and research institutions. This evolution underscores the ongoing advancements in the field, promising to further elevate the success outcomes of ART and offering hope to millions facing infertility challenges.
Restraints
- Technical Challenges and Risks
- Regulatory and Ethical Concerns
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Limited Awareness and Accessibility in Emerging Markets: Expanding the cryopreservation market into emerging markets presents significant challenges due to various socio-economic and infrastructural factors. One major obstacle is the lack of adequate infrastructure to support the storage and maintenance of cryopreserved biological samples. Many emerging markets face issues with inconsistent power supply, which can jeopardize the integrity of stored samples. Additionally, the scarcity of specialized facilities, such as biobanks and fertility clinics equipped with cryopreservation technology, further impedes accessibility to these services.
A shortage of skilled professionals proficient in cryopreservation techniques exacerbates the problem. Training programs tailored to the needs of emerging markets are essential to build local expertise and ensure the proper handling of cryopreserved samples. Furthermore, limited funding and resources pose a significant barrier to the adoption of cryopreservation technology in these regions. Governments, non-profit organizations, and international agencies need to allocate resources to support the establishment of cryopreservation facilities and research initiatives, thereby fostering the growth of the market.
Customizing marketing strategies and product offerings is crucial for successful penetration into emerging markets. This entails understanding the unique cultural, regulatory, and economic landscapes of each region and tailoring cryopreservation solutions accordingly. For example, offering more affordable and compact cryopreservation equipment suitable for smaller clinics or mobile units can increase accessibility. Collaborating with local stakeholders, including healthcare providers, researchers, and policymakers, is essential for identifying market needs and developing targeted solutions that address specific challenges faced by emerging market populations. By addressing these foundational issues and adopting a localized approach, the cryopreservation market can gradually expand its presence in emerging markets, ultimately benefiting both healthcare providers and patients in these regions.
Opportunities
- Expansion in Biobanking
- Advancements in Regenerative Medicine
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Growth in Assisted Reproductive Technology (ART): Assisted reproductive technology (ART), particularly in vitro fertilization (IVF), has become a cornerstone in addressing infertility issues globally. Cryopreservation plays a pivotal role in ART by enabling the storage of gametes (sperm and eggs) and embryos for future use, providing individuals and couples with increased flexibility and options for family planning. As infertility rates continue to rise worldwide, driven by factors such as delayed childbearing and lifestyle changes, the demand for cryopreservation equipment in fertility clinics and research institutions is expected to escalate.
The evolving landscape of ART demands not only traditional cryopreservation equipment but also innovative solutions that enhance the efficacy and efficiency of the process. These include advanced technologies that improve the survival rates of thawed samples, reducing the risk of damage and increasing the likelihood of successful fertilization and pregnancy. Moreover, automated systems for tracking and managing samples streamline the cryopreservation workflow, minimizing errors and ensuring traceability. Additionally, the development of devices that enhance the ease and safety of handling cryogenic materials addresses the challenges associated with the manipulation of ultra-low temperatures, further advancing the field of ART and improving outcomes for patients undergoing fertility treatments.
Competitive Landscape Analysis
Key players in Global Cryopreservation Equipment Market include
- Thermo Fisher Scientific, Inc.
- Custom Biogenic Systems
- Chart Biomedical Co. Ltd.
- Merck KGaA
- Barber-Nichols Inc.
- Praxair Technology, Inc.
- Linde LLC
- Planer PLC
- Cryologic Pty. Ltd.
- Charter Medicals
- Nikkiso Cryo Inc
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Equipment
- Market Snapshot, By Application
- Market Snapshot, By End Users
- Market Snapshot, By Cryogen
- Market Snapshot, By Region
- Global Cryopreservation Equipment Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Advancements in Regenerative Medicine and Cell Therapy
- Rise in Biobanking Activities
- Increased Use in Assisted Reproductive Technology (ART)
- Restraints
- Technical Challenges and Risks
- Regulatory and Ethical Concerns
- Limited Awareness and Accessibility in Emerging Markets
- Opportunities
- Expansion in Biobanking
- Advancements in Regenerative Medicine
- Growth in Assisted Reproductive Technology (ART)
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Cryopreservation Equipment Market, By Equipment, 2021 - 2031 (USD Million)
- Freezers
- Cryopreservation Freezers
- Drystore Freezers
- Incubators
- Sample Preparation Systems and Accessories
- Cryopreservation Vials
- Freezer Box
- Cryocart
- Cryogenic Vaporizer
- Others
- Freezers
- Global Cryopreservation Equipment Market, By Application, 2021 - 2031 (USD Million)
- Cord Blood Stem Cells
- Sperms, Semen & Testicular Tissues
- Embryos & Oocytes
- Others
- Global Cryopreservation Equipment Market, By End Users, 2021 - 2031 (USD Million)
- Stem Cells Banks
- Biotechnology and Pharmaceutical Organizations
- Contract Research Organizations
- Stem Cell Research Laboratories
- Research and Academic Institutes
- Global Cryopreservation Equipment Market, By Cryogen, 2021 - 2031 (USD Million)
- Liquid Nitrogen
- Oxygen
- Argon
- Liquid Helium
- Global Cryopreservation Equipment Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Cryopreservation Equipment Market, By Equipment, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Thermo Fisher Scientific, Inc.
- Custom Biogenic Systems
- Chart Biomedical Co. Ltd.
- Merck KGaA
- Barber-Nichols Inc.
- Praxair Technology, Inc.
- Linde LLC
- Planer PLC
- Cryologic Pty. Ltd.
- Charter Medicals
- Nikkiso Cryo Inc
- Company Profiles
- Analyst Views
- Future Outlook of the Market