Global Choroidal Neovascularization (CNV) Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Diagnosis;
Fluorescein Angiography, Optical Coherence Tomography, and Others.By Treatment;
Nti-VEGF, Photodynamic , Therapy, Thermal Laser, and Others.By End-Users;
Hospitals, Specialty Clinics, and Others.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Choroidal Neovascularization (CNV) Market (USD Million), 2021 - 2031
In the year 2024, the Global Choroidal Neovascularization (CNV) Market was valued at USD 7,429.48 million. The size of this market is expected to increase to USD 12,577.18 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 7.8%.
Choroidal Neovascularization (CNV) commonly occurs in individuals with diabetic retinopathy. In rare instances, it can also manifest in those with defects in Bruch's membrane, the innermost layer of the choroid. The American Academy of Ophthalmology notes a high likelihood for patients with CNV in one eye to develop CNV in the other eye within a short period. Presently, Novartis holds a license for manufacturing Ranibizumab globally, while Genentech holds the patent in the U.S. market for CNV treatment. Alongside market insights like value, growth rate, segments, geographical coverage, and players, the report from Data Bridge Market Research includes expert analysis, patient epidemiology, pipeline assessment, pricing analysis, and regulatory framework scrutiny.
Global Choroidal Neovascularization (CNV) Market Recent Developments
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In 2024, The European Medicines Agency (EMA) approved an extended dosing interval for Eylea (aflibercept), allowing for less frequent administration. This approval aligns with the trend towards longer-acting therapies and improved patient convenience
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In January 2022, Faricimab (Vabysmo), approved by the FDA in January 2022, offers extended treatment intervals, potentially reducing the frequency of injections from monthly to every two months.
Segment Analysis
In this comprehensive report, the Global Choroidal Neovascularization (CNV) Market is meticulously segmented based on Diagnosis, Treatment, End-Users, and Geography, providing a detailed understanding of the multifaceted landscape of CNV management and care.
The segmentation by Diagnosis encompasses various methods used to detect and evaluate CNV, including optical coherence tomography (OCT), fluorescein angiography (FA), indocyanine green angiography (ICGA), and fundus photography. These diagnostic modalities enable healthcare providers to accurately assess the extent and characteristics of CNV lesions, facilitating treatment planning and monitoring of disease progression.
Furthermore, the segmentation by Treatment delineates the diverse therapeutic interventions available for CNV management, including anti-vascular endothelial growth factor (anti-VEGF) injections, photodynamic therapy (PDT), laser therapy, and surgical interventions such as vitrectomy. Each treatment modality offers unique benefits and considerations, tailored to the individual needs and clinical presentation of CNV patients.
The segmentation by End-Users reflects the broad spectrum of healthcare providers and institutions involved in CNV diagnosis, treatment, and management, including ophthalmology clinics, hospitals, ambulatory surgical centers, and research institutes. Each end-user category plays a vital role in delivering comprehensive care to CNV patients, spanning from early detection and diagnosis to ongoing treatment and long-term follow-up.
Geographically, the segmentation captures regional variations in CNV prevalence, treatment practices, and healthcare infrastructure, enabling stakeholders to tailor their strategies and interventions to address specific market dynamics and patient needs across different geographical regions.
By providing a detailed segmentation framework, this report equips stakeholders with actionable insights to navigate the complexities of the Global Choroidal Neovascularization (CNV) Market effectively. It facilitates informed decision-making, strategic planning, and targeted interventions aimed at improving patient outcomes and advancing the field of CNV diagnosis and treatment on a global scale.
Global Choroidal Neovascularization (CNV) Segment Analysis
In this report, the Global Choroidal Neovascularization (CNV) Market has been segmented by Diagnosis, Treatment, End-Users and Geography.
Global Choroidal Neovascularization (CNV) Market, Segmentation by Diagnosis
The Global Choroidal Neovascularization (CNV) Market has been segmented by Diagnosis into Fluorescein Angiography, Optical Coherence Tomography and Others.
Fluorescein Angiography (FA) remains a cornerstone diagnostic tool in the assessment of CNV, offering real-time visualization of retinal vasculature and the detection of abnormal vascular leakage characteristic of CNV lesions. By injecting a fluorescent dye into the bloodstream and capturing sequential images of the retina, FA provides valuable information about the size, location, and activity of CNV lesions, facilitating accurate diagnosis and treatment planning.
Optical Coherence Tomography (OCT) has emerged as another indispensable diagnostic modality for CNV, offering high-resolution, cross-sectional imaging of retinal layers and substructures. OCT enables detailed visualization of CNV morphology, including subretinal fluid accumulation, retinal pigment epithelium detachment, and fibrovascular membrane formation. With its non-invasive nature and ability to quantify disease severity, OCT plays a crucial role in monitoring CNV progression, assessing treatment response, and guiding therapeutic decision-making.
Additionally, the "Others" category encompasses supplementary diagnostic techniques such as indocyanine green angiography (ICGA), fundus photography, and visual acuity testing, which may complement FA and OCT findings in certain clinical scenarios. These ancillary tests provide additional insights into CNV characteristics, vascular perfusion patterns, and functional visual outcomes, further enhancing the diagnostic accuracy and comprehensive evaluation of CNV patients.
By segmenting the Global Choroidal Neovascularization (CNV) Market based on these diagnostic modalities, stakeholders gain valuable insights into the diverse approaches utilized in CNV diagnosis, enabling tailored and effective management strategies to optimize patient outcomes and preserve visual function.
Global Choroidal Neovascularization (CNV) Market, Segmentation by Treatment
The Global Choroidal Neovascularization (CNV) Market has been segmented by Treatment into nti-VEGF, Photodynamic, Therapy, Thermal Laser and Others.
Anti-VEGF therapy represents a cornerstone in the treatment of CNV, involving the administration of medications that inhibit vascular endothelial growth factor (VEGF), a key driver of CNV pathogenesis. Drugs like ranibizumab, aflibercept, and bevacizumab are commonly used to reduce vascular leakage, suppress neovascularization, and improve visual outcomes in CNV patients. Anti-VEGF injections are typically administered intravitreally at regular intervals, allowing for sustained suppression of CNV activity and preservation of visual function over time.
Photodynamic Therapy (PDT) offers an alternative treatment approach for CNV, particularly in cases where anti-VEGF therapy may be less effective or contraindicated. PDT involves the intravenous administration of a photosensitizing agent, followed by focal laser irradiation of CNV lesions to induce localized vascular occlusion and reduce abnormal neovascularization. PDT is particularly beneficial in cases of predominantly classic CNV lesions, where precise targeting of abnormal blood vessels is crucial for therapeutic success.
Thermal Laser therapy involves the application of laser energy to CNV lesions, leading to selective photocoagulation and closure of abnormal blood vessels. While less commonly used today due to the advent of more targeted and less invasive treatment modalities such as anti-VEGF therapy and PDT, thermal laser remains a viable option in certain cases of CNV, particularly when other treatments are not feasible or effective.
The "Others" category encompasses supplementary treatment modalities such as corticosteroids, combination therapies, and experimental interventions that may be employed in select cases of CNV resistant to conventional treatments or in conjunction with primary therapies to enhance treatment outcomes.
By segmenting the Global Choroidal Neovascularization (CNV) Market based on these treatment modalities, stakeholders gain valuable insights into the diverse approaches available for managing CNV, enabling personalized treatment strategies tailored to the individual needs and characteristics of CNV patients.
Global Choroidal Neovascularization (CNV) Market, Segmentation by End-Users
The Global Choroidal Neovascularization (CNV) Market has been segmented by End-Users into Hospitals, Specialty Clinics and Others.
Hospitals serve as key hubs for CNV diagnosis and treatment, offering a wide range of medical services and specialized facilities to address the complex needs of CNV patients. Ophthalmology departments within hospitals are equipped with advanced diagnostic equipment, treatment modalities, and multidisciplinary teams of ophthalmologists, retina specialists, nurses, and support staff trained in managing CNV cases. Hospitals play a central role in providing comprehensive CNV care, from initial diagnosis and treatment initiation to long-term follow-up and monitoring.
Specialty Clinics dedicated to ophthalmic care represent another essential segment of the CNV healthcare landscape. These clinics focus exclusively on eye-related conditions, including CNV, and offer specialized expertise, state-of-the-art technology, and personalized care tailored to the unique needs of CNV patients. Specialty clinics often provide a more streamlined and focused approach to CNV diagnosis and treatment, enabling efficient care delivery and specialized interventions optimized for optimal visual outcomes.
The "Others" category encompasses a diverse range of healthcare settings beyond hospitals and specialty clinics, including ambulatory surgical centers, academic medical centers, and research institutions involved in CNV research, clinical trials, and tertiary care services. While hospitals and specialty clinics play primary roles in delivering frontline CNV care, other healthcare settings contribute to the broader ecosystem of CNV management through specialized services, collaborative research efforts, and innovative treatment modalities.
By segmenting the Global Choroidal Neovascularization (CNV) Market based on these end-users, stakeholders gain valuable insights into the distribution of CNV care and the role of different healthcare settings in delivering comprehensive and personalized services to CNV patients. This segmentation facilitates strategic planning, resource allocation, and targeted interventions aimed at optimizing CNV care delivery and improving patient outcomes across diverse healthcare environments.
Global Choroidal Neovascularization (CNV) Market, Segmentation by Geography
In this report, the Global Choroidal Neovascularization (CNV) Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Choroidal Neovascularization (CNV) Market Share (%), by Geographical Region, 2024
North America represents a prominent market for CNV management, characterized by advanced healthcare infrastructure, high prevalence of age-related macular degeneration (AMD), and robust research and development activities in ophthalmology. The region is home to key market players, advanced diagnostic and treatment modalities, and a well-established regulatory framework, driving innovation and adoption of novel CNV therapies. Moreover, increasing healthcare expenditure, growing awareness about eye health, and favorable reimbursement policies further contribute to the growth of the CNV market in North America.
Europe is another significant region in the Global CNV Market, characterized by a large patient population, technological advancements in ophthalmic care, and a strong emphasis on evidence-based medicine. Countries like the UK, Germany, France, and Italy exhibit a high prevalence of AMD and diabetic retinopathy, driving the demand for CNV diagnosis and treatment. Additionally, collaborations between academia, industry, and healthcare institutions foster innovation and research in CNV management, propelling market growth in the region.
The Asia Pacific region holds immense potential for the CNV market, driven by factors such as the rising prevalence of age-related eye diseases, increasing healthcare investments, and expanding access to advanced ophthalmic care. Countries like China, Japan, and India are witnessing rapid urbanization, aging populations, and improving healthcare infrastructure, creating opportunities for market expansion. Moreover, strategic initiatives by governments and healthcare organizations to address the burden of blindness and vision impairment contribute to the growth of the CNV market in Asia Pacific.
In the Middle East and Africa (MEA) and Latin America regions, the CNV market is characterized by evolving healthcare systems, improving access to eye care services, and growing awareness about retinal diseases. Despite challenges such as limited healthcare resources and infrastructure, initiatives aimed at early detection, treatment access, and capacity building are driving market growth in these regions. Collaborative efforts between governments, NGOs, and international organizations further support the expansion of CNV care in MEA and Latin America.
By segmenting the Global Choroidal Neovascularization (CNV) Market based on geography, stakeholders gain valuable insights into regional variations, market dynamics, and growth opportunities, enabling informed decision-making, strategic planning, and targeted interventions to address the diverse needs of CNV patients worldwide.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Choroidal Neovascularization (CNV) Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers :
- Rising Prevalence of Age-Related Macular Degeneration (AMD)
- Growing Geriatric Population
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Technological Advancements - The Global Choroidal Neovascularization (CNV) Market is experiencing significant growth driven by technological advancements in diagnostic and treatment modalities. Innovations in imaging technologies such as Optical Coherence Tomography Angiography (OCTA) and enhanced Fluorescein Angiography (FA) have revolutionized the early detection and detailed characterization of CNV. These advanced imaging techniques provide high-resolution, non-invasive visualization of retinal and choroidal structures, allowing for precise assessment of CNV lesions, monitoring of disease progression, and evaluation of treatment efficacy. This technological leap has enabled clinicians to make more informed decisions and tailor treatments to individual patient needs, thereby improving clinical outcomes and patient quality of life.
On the treatment front, advancements in pharmacotherapy and delivery methods have significantly impacted the CNV market. The development of sustained-release anti-VEGF formulations and novel drug delivery systems, such as intravitreal implants and biodegradable microspheres, has enhanced the therapeutic landscape. These innovations aim to reduce the frequency of intravitreal injections, improving patient compliance and convenience. Additionally, research into gene therapy and regenerative medicine holds promise for future breakthroughs in CNV management, potentially offering long-lasting and even curative solutions. These technological advancements not only drive market growth but also underscore the commitment to improving the standard of care for patients with CNV, highlighting a dynamic and evolving field poised for continued innovation.
Restraints :
- High Cost of Treatments
- Limited Availability of Skilled Ophthalmologists
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Reimbursement Issues - The Global Choroidal Neovascularization (CNV) Market faces significant challenges related to reimbursement issues, which can impact patient access to advanced treatments and overall market growth. Reimbursement policies vary widely across different regions and healthcare systems, creating disparities in the availability and affordability of CNV therapies. In many countries, the high cost of anti-VEGF treatments, which are the standard of care for CNV, poses a substantial financial burden on both healthcare providers and patients. These costs are often exacerbated by the need for repeated treatments over time to maintain visual acuity and control disease progression.
Moreover, complex and stringent reimbursement procedures can lead to delays in treatment initiation, negatively affecting patient outcomes. Insurance coverage limitations and varying criteria for reimbursement eligibility further complicate access to CNV therapies. In regions where public health insurance is limited or non-existent, out-of-pocket expenses can be prohibitively high, deterring patients from seeking necessary care. To address these challenges, there is a growing need for policy reforms, increased funding for public health programs, and collaborative efforts between healthcare providers, policymakers, and pharmaceutical companies to develop sustainable reimbursement models. These measures are crucial to ensuring equitable access to effective CNV treatments and improving the overall management of the condition on a global scale.
Opportunity :
- Emerging Markets
- Focus on Early Detection
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Research and Development - The Global Choroidal Neovascularization (CNV) Market is witnessing significant advancements driven by intensive research and development (R&D) efforts. These initiatives are focused on enhancing our understanding of CNV pathophysiology, developing novel therapeutic approaches, and improving diagnostic techniques. Leading pharmaceutical companies, academic institutions, and research organizations are investing heavily in R&D to innovate and refine treatments that can effectively address the complexities of CNV, with the ultimate goal of preserving and restoring vision in affected individuals.
A key area of R&D in the CNV market is the development of next-generation anti-VEGF therapies, which aim to provide longer-lasting effects and improved patient outcomes. Researchers are also exploring combination therapies that integrate anti-VEGF agents with other treatments, such as corticosteroids or novel biologics, to enhance efficacy and reduce treatment resistance. Additionally, advancements in gene therapy and regenerative medicine hold promise for offering new solutions to CNV patients. Diagnostic technologies are also evolving, with improvements in imaging modalities such as optical coherence tomography (OCT) and the development of more precise biomarkers aiding in earlier and more accurate detection of CNV. These R&D efforts are crucial for advancing the field, offering hope for better management of CNV, and potentially leading to breakthroughs that could transform patient care in the coming years.
Competitive Landscape Analysis
Key players in Global Choroidal Neovascularization (CNV) Market include
- Novartis AG
- Regeneron
- Sanofi
- Genentech Inc
- Bayer AG
- Chengdu Kanghong Biotech Co. Ltd
- Resolvyx Pharmaceuticals Inc
- F. Hoffmann-La Roche Ltd
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Diagnosis
- Market Snapshot, By Treatment
- Market Snapshot, By End-Users
- Market Snapshot, By Region
- Global Choroidal Neovascularization (CNV) Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Rising Prevalence of Age-Related Macular Degeneration (AMD)
- Growing Geriatric Population
- Technological Advancements
- Restraints
- High Cost of Treatments
- Limited Availability of Skilled Ophthalmologists
- Reimbursement Issues
- Opportunities
- Emerging Markets
- Focus on Early Detection
- Research and Development
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
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Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Choroidal Neovascularization (CNV) Market, By Diagnosis, 2021 - 2031 (USD Million)
- Fluorescein Angiography
- Optical Coherence Tomography,
- Others
- Global Choroidal Neovascularization (CNV) Market, By Treatment, 2021 - 2031 (USD Million)
- Nti-VEGF
- Photodynamic
- Therapy
- Thermal Laser
- Others
- Global Choroidal Neovascularization (CNV) Market, By End-Users, 2021 - 2031 (USD Million)
- Hospitals
- Specialty Clinics,
- Others
- Global Choroidal Neovascularization (CNV) Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Choroidal Neovascularization (CNV) Market, By Diagnosis, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Novartis AG
- Regeneron
- Sanofi
- Genentech Inc
- Bayer AG
- Chengdu Kanghong Biotech Co. Ltd
- Resolvyx Pharmaceuticals Inc
- F. Hoffmann-La Roche Ltd
- Company Profiles
- Analyst Views
- Future Outlook of the Market