Global Cell Isolation/Cell Separation Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Product;
Consumables - Reagents, Kits, Media, and Sera, Beads, Disposables, and Instruments - Centrifuges, Flow Cytometers, Filtration Systems, and Magnetic-activated Cell Separator Systems.By Type;
Human Cells and Animal Cells.By Technique;
Centrifugation, Surface Marker, and Filtration.By Application;
Biomolecule Isolation, Cancer Research, Stem Cell Research, Tissue Regeneration, In Vitro Diagnostics, and Therapeutics.By End User;
Research Laboratories & Institutes, Hospitals & Diagnostic Laboratories, Cell Banks, and Biotechnology & Biopharmaceutical Companies.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Cell Isolation/Cell Separation Market (USD Million), 2021 - 2031
In the year 2023, the Global Cell Isolation/Cell Separation Market was valued at USD 9,710.08 million. The size of this market is expected to increase to USD 28,554.63 million by the year 2030, while growing at a Compounded Annual Growth Rate (CAGR) of 16.7%.
Cell separation is a critical process employed across various applications such as biologics designing, therapeutic protein production, in-vitro diagnostics, and research endeavors. The market is experiencing robust growth driven by the increasing prevalence of chronic and infectious diseases like cancer and COVID-19, coupled with ongoing government initiatives aimed at bolstering the biotechnology industry. Product innovation stands out as a key driver fostering market expansion.
Leading companies in the field, including NanoString Technologies, Levitas Bio, and Bionano Genomics, are actively engaged in product development initiatives to broaden their offerings. For instance, Levitas Bio recently introduced the LeviCell EOS System in April 2022, a next-generation platform for cell separation boasting enhanced throughput and targeted selection capabilities. The COVID-19 pandemic has further underscored the importance of cell separation tools in research applications, as evidenced by increased funding for R&D, such as the USD 3 billion allocated by the U.S. government in March 2020 for vaccine development, medical treatments, and test kits.
The growing demand for biologics, including monoclonal antibodies and recombinant proteins, is also fueling the adoption of cell separation techniques. With the burgeoning specialty drugs market and personalized medicine, biologics are witnessing heightened demand. Moreover, the influx of funding and surging demand have spurred the entry of startups into the cell separation industry, despite the high costs associated with research and development. For example, Veeda Group, in collaboration with Atal Incubation Centre - Centre for Cellular and Molecular Biology (AIC - CCMB), organized a symposium in Hyderabad in October 2023 focused on addressing development challenges and accelerating timelines for emerging biopharmaceuticals.
Global Cell Isolation/Cell Separation Market Recent Developments
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In October 2022, Thermo Fisher Scientific, Inc. unveiled DynaCellect, an advanced instrument designed for cell isolation, activation, and depletion, marking a significant leap in cell therapy manufacturing capabilities. Alongside DynaCellect, the company also introduced the Dynabeads magnetic beads removal instrument, aimed at streamlining the cell therapy manufacturing process. These innovations represent Thermo Fisher's commitment to advancing bioprocessing technologies and addressing the evolving needs of the cell therapy industry.
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In June 2022, Terumo BCT and GenCure joined forces to propel the development of cutting-edge solutions for cell and gene therapy manufacturing. By leveraging their respective expertise and resources, the collaboration aims to accelerate the advancement of manufacturing processes essential for the production of innovative cell and gene therapies. This strategic partnership underscores the industry's collective efforts to overcome manufacturing challenges and drive progress in the field of regenerative medicine.
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In May 2022, Terumo BCT celebrated the inauguration of its second manufacturing facility in Colorado, a milestone event signaling the company's commitment to expanding its manufacturing capabilities and meeting the growing demand for cell therapy products. The new facility is poised to bolster Terumo BCT's production capacity, enabling it to address the increasing needs of the cell therapy market effectively. This expansion aligns with Terumo BCT's overarching mission to support advancements in healthcare through innovative manufacturing solutions.
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In January 2022, Sony Corporation made a significant stride in the field of cell isolation with the launch of CGX10, an innovative cell isolation system. This cutting-edge technology represents a significant advancement in the industry, offering capabilities for sorting cells with exceptional speed and purity. One of the key features of the CGX10 system is its ability to operate within a closed system, providing a controlled environment that minimizes the risk of contamination and ensures the integrity of the isolated cells.
Segment Analysis
Cell isolation, various products play crucial roles in facilitating the process. Consumables such as reagents, kits, media, and sera are fundamental components utilized in cell isolation protocols, providing essential nutrients and growth factors for cell culture and maintenance. Beads and disposables are also essential consumables used for cell separation techniques, enabling the selective isolation of target cells from complex biological samples. On the other hand, instruments like centrifuges, flow cytometers, filtration systems, and magnetic-activated cell separator systems are indispensable tools employed to streamline and automate the cell isolation process, ensuring efficiency and reproducibility.
The types of cells being isolated are another significant aspect of cell isolation procedures. Human cells and animal cells represent distinct categories with unique characteristics and applications. Human cells are often isolated for therapeutic purposes, diagnostic testing, and research in areas such as regenerative medicine and cancer biology. Animal cells, on the other hand, are frequently utilized in preclinical studies, drug development, and fundamental research across various biological disciplines.
Techniques employed in cell isolation play a pivotal role in determining the success and efficiency of the process. Centrifugation, surface marker-based methods, and filtration are among the most commonly used techniques. Centrifugation techniques rely on the differential sedimentation of cells based on their density, while surface marker-based methods utilize specific markers on cell surfaces to selectively isolate target cells. Filtration techniques involve the physical separation of cells based on size, allowing for the isolation of cells of interest from heterogeneous cell populations.
The applications of cell isolation techniques span a wide range of fields, including biomolecule isolation, cancer research, stem cell research, tissue regeneration, in vitro diagnostics, and therapeutics. These applications highlight the versatility and importance of cell isolation in advancing biomedical research, diagnostics, and therapeutic interventions. Moreover, the end users of cell isolation products and services include research laboratories and institutes, hospitals and diagnostic laboratories, cell banks, as well as biotechnology and biopharmaceutical companies, underscoring the broad impact and relevance of cell isolation across diverse sectors of the life sciences industry.
Global Cell Isolation/Cell Separation Segment Analysis
In this report, the Global Cell Isolation/Cell Separation Market has been segmented by Product, Type, Technique, Application, End User, and Geography.
Global Cell Isolation/Cell Separation Market, Segmentation by Product
The Global Cell Isolation/Cell Separation Market has been segmented by Product into Consumables and Instruments.
In 2023, the consumables segment emerged as the frontrunner in the market. This dominance is primarily attributed to the frequent and repeated purchases of consumables required for various cell separation processes. The consistent demand for consumables is fueled by the increasing investments in research and development (R&D) activities undertaken by pharmaceutical and biopharmaceutical companies. These investments are directed towards the development of advanced biologics, including monoclonal antibodies and vaccines, which necessitate a continuous supply of consumables. As such, the consumables segment is expected to maintain its stronghold in the market throughout the forecast period, driven by the sustained demand from the pharmaceutical and biopharmaceutical sectors.
The instruments segment is poised to exhibit a lucrative growth rate in the forecast period, propelled by various advancements in product technology. These technological advancements enable more efficient cell separation processes across research, diagnostics, and therapeutic applications. As a result, the demand for advanced instruments is anticipated to surge in the coming years. Despite the optimistic growth outlook, the high cost associated with instruments may act as a hindrance, potentially restraining market growth to some extent. Nevertheless, the increasing emphasis on technological innovation by industry players is expected to mitigate these challenges and drive significant growth in the instruments segment.
To gain a competitive edge in the market, companies are increasingly focusing on developing sustainable technology solutions. An illustrative example of this is the unveiling of the Aviti DNA sequencing platform by Element Biosciences in March 2022. This forthcoming benchtop instrument is anticipated to revolutionize the industry by reducing reagent usage and cutting down costs significantly, to approximately USD 7 per gigabase (Gb). Such initiatives underscore the industry's commitment to sustainability and cost-effectiveness, thereby shaping the future landscape of the cell separation market.
Global Cell Isolation/Cell Separation Market, Segmentation by Type
The Global Cell Isolation/Cell Separation Market has been segmented by Type into Human Cells and Animal Cells.
In 2023, the animal cells segment emerged as the leader in the market. This dominance is primarily attributed to the growing focus of government entities, private organizations, and healthcare companies on new drug discoveries and development. Animal cells play a crucial role in drug discovery and development processes, where they are used to examine the efficacy, pharmacokinetics, and preliminary toxicity of new drug molecules. As a result, the increasing emphasis on drug development activities is driving significant demand for animal cell isolation techniques, thereby bolstering the growth of this segment.
The human cells segment is poised to exhibit the fastest growth rate 2024 to 2030, signaling promising opportunities in the market. This rapid growth trajectory is driven by several factors, including the rising focus on human and cancer research, as well as the diverse applications of isolated human cells in biopharmaceutical development, clinical trials, and research activities. Moreover, favorable reimbursement policies pertaining to personalized medicine in developed countries further contribute to the growing demand for human cell isolation techniques. As personalized medicine gains traction, the need for precise isolation and characterization of human cells becomes paramount, thereby fueling the expansion of this segment.
Global Cell Isolation/Cell Separation Market, Segmentation by Technique
The Global Cell Isolation/Cell Separation Market has been segmented by Technique into Centrifugation, Surface Marker, and Filtration.
In 2023, the centrifugation segment emerged as the dominant force in the market. This segment's dominance can be attributed to the widespread utilization of centrifugation techniques across various sectors, including academic institutes, research laboratories, and biotechnology and biopharmaceutical companies. Centrifugation plays a vital role in the cell isolation and separation process, facilitating the efficient separation of cells based on their density or size. Notably, density gradient centrifugation and differential centrifugation techniques are among the most commonly employed methods for cell isolation and separation, underscoring the significance of centrifugation in the field of cell separation.
The surface marker technique is poised to exhibit the fastest growth rate from 2024 to 2030, signaling promising opportunities in the market. This accelerated growth trajectory is fueled by several factors, including increasing investments in manufacturing infrastructure by companies and continuous product advancements. Manufacturers are increasingly focusing on leveraging advanced surface markers for cell isolation and separation processes, aiming to enhance the quality and efficiency of the end products. As a result, the surface marker technique is witnessing heightened adoption across various industries, driving its rapid growth within the cell separation market.
Global Cell Isolation/Cell Separation Market, Segmentation by Application
The Global Cell Isolation/Cell Separation Market has been segmented by Application into Biomolecule Isolation, Cancer Research, Stem Cell Research, Tissue Regeneration, In Vitro Diagnostics and Therapeutics.
In 2023, the biomolecule isolation segment emerged as the dominant force in the market. This segment also demonstrated strong growth momentum and is expected to maintain its position as the fastest-growing segment from 2024 to 2030. The remarkable growth of the biomolecule isolation segment can be attributed to several factors. Primarily, there is a growing emphasis on the production of biopharmaceuticals, including biosimilars, monoclonal antibodies, and recombinant proteins, which are driving the demand for advanced cell separation solutions. Additionally, increasing government funding for new drug development initiatives is further propelling the growth of this segment. These factors collectively contribute to the dominance and continued expansion of the biomolecule isolation segment within the cell separation market.
The cancer research segment is poised to exhibit lucrative growth from 2024 to 2030. This growth trajectory is fueled by rising investments in cell-based research by companies and research laboratories, driven by the increasing global incidence of cancer. Public-private organizations are channeling significant investments into cancer research initiatives, thereby creating a heightened demand for innovative cell separation solutions tailored for cancer research applications. Moreover, the emergence of precision medicine for cancer treatment represents a significant opportunity for market growth. For instance, PerkinElmer's expansion of its offering with advanced technology for cancer research is expected to bolster the cancer research segment, further contributing to market expansion.
Global Cell Isolation/Cell Separation Market, Segmentation by End User
The Global Cell Isolation/Cell Separation Market has been segmented by End User into Research Laboratories & Institutes, Hospitals & Diagnostic Laboratories, Cell Banks, and Biotechnology & Biopharmaceutical Companies.
The biotechnology and biopharmaceutical companies segment maintained its dominant position in the cell separation market. This segment is projected to sustain its leading position throughout the study period. The robust growth of this segment can be attributed to the extensive research and development (R&D) activities undertaken by biotechnology and biopharmaceutical firms to innovate new-generation therapeutics. These innovative therapies often require sophisticated cell separation techniques, driving the demand for advanced cell separation solutions. Moreover, the surge in research activities by commercial organizations aimed at developing effective vaccines and therapeutics for COVID-19 is expected to further fuel the demand for cell separation technologies, thereby contributing to the growth of this segment.
The research laboratories and institutes segment are poised to witness steady growth. This growth can be attributed to the increasing R&D initiatives undertaken by research institutions, particularly in areas such as oncology and neuroscience, to develop novel therapies. The expanding number of research institutes and laboratories worldwide is expected to be a significant driver of segment growth. For example, in April 2022, Curate Biosciences partnered with the City of Hope, a renowned cancer research and treatment organization in the U.S., to evaluate Curate's Cell Processing System for advanced cell separation. The collaboration aims to integrate this platform into existing workflows to streamline the production of CAR-T cell immunotherapy, highlighting the growing emphasis on enhancing cell separation capabilities in research settings.
Global Cell Isolation/Cell Separation Market, Segmentation by Geography
In this report, the Global Cell Isolation/Cell Separation Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Cell Isolation/Cell Separation Market Share (%), by Geographical Region, 2024
North America asserted its dominance in the global cell separation market by commanding the largest revenue share. This leadership position can be attributed to several key factors. Firstly, the region boasts well-established pharmaceutical and biotechnology industries, particularly in the United States, which have been early adopters of technologically advanced solutions for various applications, including cell separation. The high level of technological sophistication in these industries has driven the demand for innovative cell separation solutions. Additionally, the presence of leading research universities and institutions in North America has fueled extensive research activities in the field of cell therapies, creating a substantial demand for advanced cell separation technologies. Moreover, the region's high prevalence of chronic and infectious diseases, compounded by the outbreak of COVID-19, has further intensified the demand for cell separation solutions for both research and clinical applications, thereby contributing to North America's market dominance.
Asia Pacific is poised to exhibit the fastest growth in the cell separation market from 2024 to 2030. Several factors are driving this robust growth trajectory in the region. Firstly, emerging economies such as China and India are witnessing rapid growth in their pharmaceutical and biotechnology industries, supported by favorable government policies and increasing investments in healthcare infrastructure. As a result, there is a growing demand for advanced technologies, including cell separation solutions, to support research and development activities in these countries. Furthermore, the expansion of healthcare expenditure across the Asia Pacific region, coupled with the increasing market penetration of major global players, is expected to further drive market growth. Additionally, ongoing initiatives in stem cell and gene therapy research in countries like Japan, China, and South Korea have significantly boosted the demand for cell separation solutions, positioning Asia Pacific as a key growth engine for the global cell separation market.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Cell Isolation/Cell Separation Market. These factors include; Market Drivers, Restraints and Opportunities.
Drivers, Restraints and Opportunities Analysis
Drivers:
- Rising Incidence of Chronic Diseases
- Increased government funding for cell-based research
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Advancements in Stem Cell Research - Stem cell research is poised to be a driving force in advancing the field of cell separation, thus fostering market growth. The increasing focus on stem cell research is attributed to its potential applications in personalized medicines and regenerative therapies. For example, researchers are utilizing a combination of cytokines, including hepatocyte growth factor (HGF), oncostatin M (OSM), epidermal growth factor (EGF), fibroblast growth factor-2 (FGF2), and leukemia inhibitory factor (LIF), to guide mesenchymal stem cells towards a hepatocyte-like cell fate. Additionally, cytokines like Activin A play a crucial role in directing induced pluripotent stem cells and embryonic stem cells into endoderm cells, highlighting the diverse applications of stem cells in regenerative medicine. Increasing investments in stem cell research are playing a significant role in expanding the industry. For instance, UC Irvine's designation as one of CIRM's cell and gene therapy manufacturing facilities, with a grant of USD 2 million, empowers the campus stem cell center to advance regenerative medicine. Similarly, under the Accelerating Cures initiative, the Maryland Stem Cell Research Commission (MSCRC) has been allocated approximately USD 4 million to drive stem cell innovations within the U.S. These investments are aimed at bolstering research efforts and fostering the development of stem cell companies, with the overarching goal of translating scientific advancements into tangible therapeutic outcomes.
The emphasis on stem cell research not only fuels scientific progress but also contributes to the expansion of the cell separation market. As research endeavors uncover new insights and therapeutic applications of stem cells, the demand for advanced cell separation technologies and solutions is expected to increase. The collaborations between academic institutions, research centers, and government initiatives further accelerate innovation in stem cell research, thereby driving the growth of the cell separation industry. These synergies between research, investment, and innovation position stem cell research as a pivotal driver of market expansion within the realm of cell separation.
Restraints:
- Complexity of Techniques
- Limited Compatibility with Fragile Cell Types
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Safety & Ethical Issues - One significant restraint facing the cell separation market is the presence of safety and ethical concerns, particularly regarding the isolation of embryonic stem cells. The process of isolating embryonic stem cells involves the destruction of the embryo from which these cells are derived. This raises ethical dilemmas surrounding the destruction of human life, as embryos are considered by some to possess the potential for human development. The ethical implications of using embryonic stem cells have sparked debates and controversies within both scientific and societal spheres. Embryonic stem cells possess the inherent ability to form teratomas, which are tumors containing cells from all three germ layers. When embryonic stem cells are transplanted into a patient without proper screening or regulation, there is a risk that these cells may form tumors and potentially cause harm to the recipient.
The prospect of adverse outcomes resulting from the uncontrolled proliferation of embryonic stem cells underscores the importance of stringent safety measures and ethical considerations in their use. These safety and ethical concerns pose challenges to the widespread adoption and growth of the cell separation market, particularly in the context of embryonic stem cell isolation. Regulatory frameworks and guidelines governing the use of embryonic stem cells vary across jurisdictions, further complicating the landscape for researchers and industry stakeholders. As a result, the uncertainty and controversy surrounding the ethical and safety implications of embryonic stem cell research can potentially hinder market growth, as stakeholders navigate these complex ethical and regulatory landscapes. Addressing these concerns through transparent communication, robust safety protocols, and adherence to ethical guidelines will be essential for overcoming these barriers and fostering sustainable growth within the cell separation market.
Opportunities:
- Advancements in Cancer Research and Therapy
- Expansion of Regenerative Medicine
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Integration of Artificial Intelligence (AI) and Automation - The integration of Artificial Intelligence (AI) and automation presents significant opportunities for advancing cell isolation techniques. AI-driven algorithms have the potential to enhance the efficiency and accuracy of cell isolation processes by analyzing vast amounts of data to identify optimal isolation protocols. By leveraging machine learning algorithms, researchers can develop predictive models that optimize cell isolation parameters based on various factors such as cell type, sample characteristics, and desired outcomes. This capability enables researchers to streamline the isolation process, reduce experimental variability, and improve the overall yield and purity of isolated cells. Automation technologies can complement AI-driven algorithms by enabling high-throughput and reproducible cell isolation workflows. Automated platforms equipped with robotic arms, liquid handling systems, and integrated sensors can perform complex isolation procedures with precision and consistency.
By automating repetitive tasks such as sample preparation, cell sorting, and data analysis, researchers can significantly increase throughput and accelerate the pace of research. Additionally, automated systems can operate around the clock, enabling continuous processing of samples and maximizing laboratory efficiency. Together, the integration of AI and automation holds promise for revolutionizing cell isolation techniques, enabling researchers to achieve higher throughput, reproducibility, and scalability in their experiments.
Competitive Landscape Analysis
Key players in Global Cell Isolation/Cell Separation Market include:
- Thermo Fisher Scientific, Inc.
- BD
- Danaher
- Terumo Corp.
- STEMCELL Technologies Inc.
- Bio-Rad Laboratories, Inc.
- Merck KgaA
- Agilent Technologies, Inc.
- Corning Inc.
- Akadeum Life Sciences
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Product
- Market Snapshot, By Type
- Market Snapshot, By Technique
- Market Snapshot, By Application
- Market Snapshot, By End User
- Market Snapshot, By Region
- Global Cell Isolation/Cell Separation Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Rising Incidence of Chronic Diseases
- Increased Government Funding for Cell-based Research
- Advancements in Stem Cell Research
- Restraints
- Complexity of Techniques
- Limited Compatibility with Fragile Cell Types
- Safety & Ethical Issues
- Opportunities
- Advancements in Cancer Research and Therapy
- Expansion of Regenerative Medicine
- Integration of Artificial Intelligence (AI) and Automation
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Competitive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Cell Isolation/Cell Separation Market, By Product, 2021 - 2031 (USD Million)
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Consumables
- Reagents, Kits, Media, and Sera
- Beads
- Disposables
- Instruments
- Centrifuges
- Flow Cytometers
- Filtration Systems
- Magnetic-activated Cell Separator Systems
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- Global Cell Isolation/Cell Separation Market, By Type, 2021 - 2031 (USD Million)
- Human Cells
- Animal Cells
- Global Cell Isolation/Cell Separation Market, By Technique, 2021 - 2031 (USD Million)
- Centrifugation
- Surface Marker
- Filtration
- Global Cell Isolation/Cell Separation Market, By Application, 2021 - 2031 (USD Million)
- Biomolecule Isolation
- Cancer Research
- Stem Cell Research
- Tissue Regeneration
- In Vitro Diagnostics
- Therapeutics
- Global Cell Isolation/Cell Separation Market, By End User, 2021 - 2031 (USD Million)
- Research laboratories and institutes
- Biotechnology and biopharmaceutical companies
- Hospitals and diagnostic laboratories
- Cell banks
- Global Cell Isolation/Cell Separation Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Cell Isolation/Cell Separation Market, By Product, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- Thermo Fisher Scientific, Inc.
- BD
- Danaher
- Terumo Corp.
- STEMCELL Technologies Inc.
- Bio-Rad Laboratories, Inc.
- Merck KgaA
- Agilent Technologies, Inc.
- Corning Inc.
- Akadeum Life Sciences
- Company Profiles
- Analyst Views
- Future Outlook of the Market