Global Cancer Biologics Market Growth, Share, Size, Trends and Forecast (2025 - 2031)
By Type;
Monoclonal Antibodies, Vaccines, Cell and Gene Therapy and Others.By Drug Class;
Monoclonal Antibodies, Cancer Growth Inhibitors, Vaccines, Recombinants Proteins, CAR-T Cells, Angiogenesis Inhibitors, Interleukins, Interferons, Gene Therapy, and Others.By Applications;
Blood Cancer, Lung Cancer, Breast Cancer, Colorectal Cancer, Prostate Cancer, Gastric Cancer, Ovarian Cancer, Skin Cancer, Liver Cancer, and Others.By Geography;
North America, Europe, Asia Pacific, Middle East and Africa and Latin America - Report Timeline (2021 - 2031).Introduction
Global Cancer Biologics Market (USD Million), 2021 - 2031
In the year 2024, the Global Cancer Biologics Market was valued at USD 92,164.13 million. The size of this market is expected to increase to USD 158,979.73 million by the year 2031, while growing at a Compounded Annual Growth Rate (CAGR) of 8.1%.
The global market for cancer biologics is witnessing significant growth driven by advancements in biotechnology and increasing prevalence of cancer worldwide. Biologics, which include monoclonal antibodies, vaccines, cytokines, and targeted therapies, are at the forefront of innovative cancer treatment approaches. These therapies leverage biological molecules to target specific cancer cells or biomarkers, offering potentially more effective and less toxic alternatives to traditional chemotherapy.
Key drivers of the global cancer biologics market include rising investments in research and development, expanding applications of biologics across various cancer types, and growing demand for personalized medicine. Biologics not only aim to inhibit cancer cell growth but also to boost the body's immune response against cancer cells, marking a paradigm shift in oncology treatment strategies.
Geographically, North America and Europe are currently leading the market due to robust healthcare infrastructure, high adoption rates of advanced therapies, and supportive regulatory frameworks. However, rapid economic development and increasing healthcare expenditure in Asia-Pacific countries are expected to fuel market growth in this region as well. Overall, the global cancer biologics market is poised for continued expansion as biotechnological innovations and personalized treatment approaches redefine the landscape of cancer care.
Global Cancer Biologics Market Recent Developments
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In 2018, National Medical Products Administration (NMPA) of China approved Sintilimab injection, which is sold under the brand name Tyvyt, and was jointly announced by Innovent Biologics, Inc. and Eli Lilly and Company.
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In 2018, pembrolizumab received approval from the U.S. Food and Drug Administration (FDA) for the treatment of patients suffering from metastatic Merkel cell carcinoma (MCC).
Segment Analysis
In terms of Drug Class, the market includes several categories, with Monoclonal Antibodies being the largest segment. These antibodies are designed to target specific proteins on cancer cells, preventing them from growing or spreading. The market is also seeing significant contributions from Cancer Growth Inhibitors, which are designed to block the signals that promote cancer cell proliferation. Vaccines, including therapeutic vaccines like those for prostate and cervical cancers, are another important drug class. Recombinant Proteins, CAR-T Cells, and Angiogenesis Inhibitors are emerging therapies that have shown promise in treating aggressive cancers. Additionally, Interleukins, Interferons, Gene Therapy, and other drug classes further enhance the diversity of cancer biologics, targeting both the tumor and the immune system to improve patient outcomes.
When segmented by Type, the market can be divided into Monoclonal Antibodies, Immune Checkpoint Inhibitors, Gene Therapy, and Cell Therapy. Monoclonal Antibodies have been a staple in cancer treatment due to their ability to specifically target tumor cells. Immune Checkpoint Inhibitors, which block proteins that prevent immune cells from attacking cancer cells, have revolutionized the treatment of various cancers, including melanoma and lung cancer. Gene Therapy offers potential by introducing genetic material into cancer cells to alter their behavior, while Cell Therapy, such as CAR-T, has been a breakthrough in the treatment of blood cancers by reprogramming a patient's own T-cells to attack cancer cells.
In terms of Application, the cancer biologics market addresses a broad range of cancer types. Blood Cancer, including leukemia and lymphoma, has seen significant advancements with CAR-T cell therapies and monoclonal antibodies. Lung Cancer treatment has been revolutionized by biologics that target specific mutations, while Breast Cancer therapies, particularly those targeting HER2-positive cancers, have proven highly effective. Other applications include Colorectal Cancer, where biologics inhibit tumor growth, and Prostate Cancer, with therapies targeting androgen receptors. Additional cancers like Gastric Cancer, Ovarian Cancer, Skin Cancer (including melanoma), and Liver Cancer are also seeing growing adoption of biologic treatments, with tailored therapies targeting the molecular characteristics of each cancer type.
Overall, the Global Cancer Biologics Market is expanding rapidly due to advances in drug classes, treatment types, and applications. With biologics offering highly targeted therapies, personalized cancer treatments are becoming more accessible, improving outcomes and survival rates across a variety of cancer types.
Global Cancer Biologics Segment Analysis
In this report, the Global Cancer Biologics Market has been segmented by Drug Class, Type, Application and Geography.
Global Cancer Biologics Market, Segmentation by Type
The Global Cancer Biologics Market has been segmented by Type into Monoclonal antibodies, Vaccines, Cell and gene therapy and Others.
Monoclonal antibodies are a significant segment within the cancer biologics market. They are engineered to target specific proteins or antigens on cancer cells, thereby aiding in immune system responses against cancer. Examples include trastuzumab (Herceptin) for HER2-positive breast cancer and rituximab (Rituxan) for certain types of lymphoma.
These are proteins that regulate immune responses and can be used therapeutically to enhance the immune system's ability to fight cancer. Interferons and interleukins are examples of cytokines used in cancer treatment to stimulate immune cells and inhibit tumor growth.
Cancer vaccines are designed to stimulate the immune system to recognize and destroy cancer cells. They can be preventive (prophylactic) or therapeutic (treatment-oriented). Examples include the human papillomavirus (HPV) vaccine for cervical cancer prevention and Sipuleucel-T (Provenge) for prostate cancer treatment.
Each type of cancer biologic has its specific mechanism of action and targets different aspects of cancer cells or the immune system. The market for these biologics continues to grow as research and development advance, leading to more effective treatments and expanded indications across various types of cancer. The segmentation helps stakeholders in the healthcare industry understand the unique characteristics and applications of each biologic type, thereby guiding treatment decisions and investments in research and development efforts.
Global Cancer Biologics Market, Segmentation by Drug Class
The Global Cancer Biologics Market has been segmented by Drug Class into Monoclonal Antibodies, Cancer Growth Inhibitors, Vaccines, Recombinants Proteins, CAR-T Cells, Angiogenesis Inhibitors, Interleukins, Interferons, Gene Therapy, and Others.
Monoclonal Antibodies are one of the most significant and widely used drug classes in cancer biologics. These antibodies are designed to target specific antigens on cancer cells, leading to direct destruction or the activation of immune responses against the tumor. Monoclonal antibodies like rituximab, trastuzumab, and pembrolizumab have revolutionized cancer treatment, especially in cancers like lymphoma, breast cancer, and melanoma.
Cancer Growth Inhibitors and Vaccines make up another important segment of the market. Cancer growth inhibitors are biologics designed to block signals that promote tumor growth, whereas vaccines such as the human papillomavirus (HPV) vaccine provide preventive measures against certain cancers like cervical cancer. Recombinant Proteins play a critical role in cancer treatment by offering proteins produced via recombinant DNA technology that aid in regulating tumor growth or improving immune response. In addition, CAR-T Cells (Chimeric Antigen Receptor T-cell therapy) have emerged as groundbreaking treatments for hematological cancers by genetically modifying a patient's T-cells to recognize and kill cancer cells.
Angiogenesis Inhibitors, Interleukins, Interferons, Gene Therapy, and Others represent other important drug classes in cancer biologics. Angiogenesis inhibitors work by blocking the blood supply to tumors, preventing their growth and spread. Interleukins and Interferons are cytokines that stimulate immune responses, used in treatments for cancers like melanoma and renal cell carcinoma. Gene Therapy involves modifying the genes inside a patient's cells to treat or prevent cancer, providing a new frontier in cancer treatment. The Others category includes additional biologics that don't fall neatly into the above classifications but still play a role in cancer therapy, often in combination with other treatments.
This segmentation demonstrates the diversity of approaches within the global cancer biologics market, with each drug class targeting different aspects of tumor growth and immune modulation to provide comprehensive treatment options.
Global Cancer Biologics Market, Segmentation by Application
The Global Cancer Biologics Market has been segmented by Application into Blood Cancer, Lung Cancer, Breast Cancer, Colorectal Cancer, Prostate Cancer, Gastric Cancer, Ovarian Cancer, Skin Cancer, Liver Cancer, and Others.
Blood Cancer, including leukemia, lymphoma, and myeloma, is a key segment in the cancer biologics market. Monoclonal antibodies, CAR-T cell therapies, and other biologic treatments are commonly used to target cancerous blood cells, offering effective treatments for these aggressive cancers. Lung Cancer is another significant application, with biologic therapies playing an important role in targeting mutations and inhibiting tumor growth. Drugs like monoclonal antibodies and targeted therapies are widely used for both small cell and non-small cell lung cancers.
Breast Cancer is a prominent application for biologic treatments, with drugs such as trastuzumab (Herceptin) and other monoclonal antibodies being essential in targeting HER2-positive cancers. The use of biologics is also growing in Colorectal Cancer, where biologic agents like bevacizumab and cetuximab are used to inhibit tumor angiogenesis and block tumor growth. In Prostate Cancer, biologics are increasingly being used in combination with other treatments to manage hormone-refractory cases and improve patient outcomes.
Other cancers in the segmentation include Gastric Cancer, Ovarian Cancer, Skin Cancer, and Liver Cancer, where biologics, particularly immunotherapies and targeted therapies, are being explored and used for advanced stages of these cancers. Gastric Cancer treatments focus on targeting specific genetic mutations, while Ovarian Cancer therapies aim to inhibit growth factors and improve patient survival. Skin Cancer, especially melanoma, has seen advancements in biologic treatments with immune checkpoint inhibitors and targeted therapies. Liver Cancer treatment involves therapies that block tumor growth or enhance the immune response against hepatocellular carcinoma. The Others category includes biologic treatments for rare and less common cancers, further highlighting the breadth of applications for cancer biologics.
This segmentation illustrates the growing role of biologic therapies in treating a wide array of cancer types, providing patients with more targeted and personalized treatment options across the oncology spectrum.
Global Cancer Biologics Market, Segmentation by Geography
In this report, the Global Cancer Biologics Market has been segmented by Geography into five regions; North America, Europe, Asia Pacific, Middle East and Africa and Latin America.
Global Cancer Biologics Market Share (%), by Geographical Region, 2024
North America holds a dominant position in the global cancer biologics market, primarily driven by the presence of advanced healthcare infrastructure, high R&D investments, and a strong emphasis on personalized medicine. The United States, in particular, leads the market with a robust biotechnology sector, extensive clinical trials, and a favorable regulatory environment that accelerates the approval of new biologic therapies. Canada also contributes to the region's growth with its increasing adoption of biologics in oncology treatments.
Europe is another key region for the cancer biologics market, characterized by well-established healthcare systems, growing awareness about biologic therapies, and supportive government initiatives for research and development. Countries like Germany, France, and the United Kingdom are major contributors, hosting numerous biotech companies and academic research institutions focused on advancing cancer biologics. The European Medicines Agency (EMA) plays a crucial role in regulating and approving biologic treatments, ensuring safety and efficacy standards are met across the region.
Asia-Pacific is witnessing rapid growth in the cancer biologics market, driven by expanding healthcare infrastructure, rising incidence of cancer, and increasing investments in biotechnology and pharmaceutical sectors. Countries such as China, India, Japan, and South Korea are pivotal in this growth, with a growing patient pool seeking advanced cancer therapies. Government initiatives to improve healthcare access and affordability, coupled with collaborations between global pharmaceutical companies and local firms, are further fueling market expansion in the region.
In summary, while North America leads in terms of market size and innovation, Europe and Asia-Pacific are emerging as lucrative markets for cancer biologics, driven by favorable regulatory environments, increasing healthcare expenditure, and rising awareness about the benefits of biologic therapies in oncology. Each region presents unique opportunities and challenges for stakeholders in the global cancer biologics market.
Market Trends
This report provides an in depth analysis of various factors that impact the dynamics of Global Cancer Biologics Market. These factors include; Market Drivers, Restraints and Opportunities Analysis.
Drivers, Restraints and Opportunity Analysis
Drivers:
- Advancements in biotechnology research
- Increasing prevalence of cancer worldwide
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Growing demand for targeted therapies - Targeted therapies, a key category within cancer biologics, are designed to interfere with specific molecules involved in cancer cell growth and survival. These therapies can include monoclonal antibodies, cancer vaccines, and other biologic agents that target specific proteins or pathways implicated in cancer progression. The specificity of these treatments enhances their effectiveness and reduces adverse effects compared to conventional treatments.
Biologics offer several advantages over traditional chemotherapy. They have the potential to be more effective because they target specific molecular pathways that drive cancer growth. This targeted approach can lead to better outcomes, such as improved survival rates and quality of life for patients. Additionally, biologics are often associated with fewer systemic side effects, such as nausea, hair loss, and immune suppression, which are common with chemotherapy.
Restraints:
- High costs associated with biologics
- Stringent regulatory requirements
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Limited accessibility in developing regions - The global cancer biologics market has witnessed significant growth and innovation, particularly in developed regions such as North America, Europe, and parts of Asia-Pacific. Biologics, including monoclonal antibodies, vaccines, and cytokines, have revolutionized cancer treatment by targeting specific molecules involved in tumor growth and immune system regulation. However, despite these advancements, access to cancer biologics remains limited in many developing regions due to several challenges.
One of the primary barriers is the high cost associated with biologic therapies. These treatments often require complex manufacturing processes and extensive research and development investments, leading to higher prices compared to traditional chemotherapy. In developing countries where healthcare budgets are limited and out-of-pocket expenses are common, the affordability of biologics becomes a significant concern. Governments and healthcare systems may struggle to allocate resources for these expensive therapies, limiting their availability to patients who could benefit from them.
Opportunities:
- Rising investments in healthcare infrastructure
- Expansion of personalized medicine
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Emerging markets in Asia-Pacific - The Asia-Pacific region is witnessing significant growth in the global cancer biologics market, driven by several key factors. Firstly, increasing cancer prevalence and a growing aging population across countries like China, India, and Japan are contributing to higher demand for advanced biologic therapies. These countries are experiencing rising incidences of various cancers, prompting healthcare providers to adopt newer biologic treatments known for their efficacy and targeted mechanisms.
Advancements in healthcare infrastructure and the increasing affordability of biologic therapies are expanding access to treatment options in Asia-Pacific. Governments and private sectors are investing in healthcare infrastructure improvements and insurance coverage, facilitating broader adoption of biologics among cancer patients. This trend is particularly notable in emerging economies where healthcare spending is rising, supporting the uptake of innovative treatments.
Competitive Landscape Analysis
Key players in Global Cancer Biologics Market include:
- AbbVie Inc.
- Hoffman-La Roche
- GlaxoSmithKline
- Eli Lilly and Company
- Amgen, Inc.
In this report, the profile of each market player provides following information:
- Company Overview and Product Portfolio
- Key Developments
- Financial Overview
- Strategies
- Company SWOT Analysis
- Introduction
- Research Objectives and Assumptions
- Research Methodology
- Abbreviations
- Market Definition & Study Scope
- Executive Summary
- Market Snapshot, By Type
- Market Snapshot, By Drug Class
- Market Snapshot, By Application
- Market Snapshot, By Region
- Global Cancer Biologics Market Dynamics
- Drivers, Restraints and Opportunities
- Drivers
- Advancements in biotechnology research
- Increasing prevalence of cancer worldwide
- Growing demand for targeted therapies
- Restraints
- High costs associated with biologics
- Stringent regulatory requirements
- Limited accessibility in developing regions
- Opportunities
- Rising investments in healthcare infrastructure
- Expansion of personalized medicine
- Emerging markets in Asia-Pacific
- Drivers
- PEST Analysis
- Political Analysis
- Economic Analysis
- Social Analysis
- Technological Analysis
- Porter's Analysis
- Bargaining Power of Suppliers
- Bargaining Power of Buyers
- Threat of Substitutes
- Threat of New Entrants
- Compititive Rivalry
- Drivers, Restraints and Opportunities
- Market Segmentation
- Global Cancer Biologics Market, By Drug Class, 2021 - 2031 (USD Million)
- Monoclonal Antibodies
- Cancer Growth Inhibitors
- Vaccines, Recombinants Proteins
- CAR-T Cells
- Angiogenesis Inhibitors
- Interleukins
- Interferons
- Gene Therapy
- Others
- Global Cancer Biologics Market, By Type, 2021 - 2031 (USD Million)
- Blood Cancer
- Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Prostate Cancer
- Gastric Cancer
- Ovarian Cancer
- Skin Cancer
- Liver Cancer
- Others
- Global Cancer Biologics Market, By Application, 2021 - 2031 (USD Million)
- Hospitals
- Clinics
- Others
- Global Cancer Biologics Market, By Geography, 2021 - 2031 (USD Million)
- North America
- United States
- Canada
- Europe
- Germany
- United Kingdom
- France
- Italy
- Spain
- Nordic
- Benelux
- Rest of Europe
- Asia Pacific
- Japan
- China
- India
- Australia & New Zealand
- South Korea
- ASEAN (Association of South East Asian Countries)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- North America
- Global Cancer Biologics Market, By Drug Class, 2021 - 2031 (USD Million)
- Competitive Landscape
- Company Profiles
- AbbVie Inc.
- Hoffman-La Roche
- GlaxoSmithKline
- Eli Lilly and Company
- Amgen, Inc.
- Company Profiles
- Analyst Views
- Future Outlook of the Market